ArticleEndocrine connections2020
Sellar surprises: a single-centre experience of unusual sellar masses.
Article in Endocrine connections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Pituitary abscess: a case report and systematic review of 488 cases.Orphanet journal of rare diseases · 2023Pooled it
- Salivary gland tissues and derived primary and metastatic neoplasms: unusual pitfalls in the work-up of sellar lesions. A systematic review.Journal of endocrinological investigation · 2021Pooled it
- Granular cell tumors of the sellar region: what should be done after subtotal resection? A systematic review.Pituitary · 2020Pooled it
- Fungal Sinusitis Spreading to the Sellar Region Mimicking a Pituitary Tumor: Case Report and Literature Review.Journal of fungi (Basel, Switzerland) · 2025Article
- Cerebrospinal fluid dissemination of an intracranial malignant peripheral nerve sheath tumor in the sellar region: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Clinical characteristics and surgical approach for pituitary granular cell tumors: a case series of six patients and literature review.Frontiers in oncology · 2025Article
- Hypopituitarism due to CNS Aspergillus Infection.Internal medicine (Tokyo, Japan) · 2024Article
- Treatment modalities and outcomes of granular cell tumors and spindle cell oncocytomas of the pituitary gland: an analysis of two national cancer databases.Acta neurochirurgica · 2024Article
- A rare case of double pituitary prolactinomas: the diagnostic application of intraoperative ultrasonography and DNA methylation markers.Archives of endocrinology and metabolism · 2024Article
- Supra-sellar granular cell tumor: Report of a case with literature review.International journal of surgery case reports · 2023Article
- Calcifying pseudoneoplasm of the neuraxis within the sellar region: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Primary glomus tumour of the pituitary gland: diagnostic challenges of a rare and potentially aggressive neoplasm.Virchows Archiv : an international journal of pathology · 2021Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost common incidentally detected sellar-suprasellar region (SSR) masses are pituitary adenomas, followed by craniopharyngioma, rathke's cleft cyst, hypophysitis, and meningioma. Besides these, certain unusual SSR lesions can sometimes present as diagnostic challenges, where diagnosis is often made post-operatively on histopathology, the pre-operative suspicion of which might have influenced the management strategies. Series describing such masses are few.
objectiveTo present clinical, biochemical, and radiological characteristics and management outcomes of rare SSR lesions other than pituitary adenomas, craniopharyngioma, rathke's cleft cyst, hypophysitis, and meningioma. DESIGN, SETTING, PATIENTS: Retrospective case record analysis of patients with uncommon SSR masses (from January 2006 to December 2016).
resultsOur series consisted of ten patients, five with neoplastic and five with non-neoplastic lesions. Neoplastic masses included granular cell tumor (n = 2), astrocytoma (n = 1), malignant peripheral nerve sheath tumor (MPNST, n = 1), and metastasis from occult papillary carcinoma of thyroid (n = 1), while non-neoplastic masses were aspergillus abscess (n = 1), sterile abscess (n = 1), and tubercular abscess (n = 1), aneurysm of left internal carotid artery (n = 1), and ruptured dermoid cyst (n = 1). All patients (except one) presented with headache and/or visual disturbance. Only one patient had acromegaly while most others had hypopituitarism. We describe detailed MRI characteristics of each of the lesion. Seven patients underwent trans-sphenoidal surgery. Post-operatively, five patients had permanent diabetes insipidus, while two patients died in early post-operative period.
conclusionOur series expand the differential diagnostic considerations of SSR lesions. Most of the rare SSR masses present with symptoms of mass effects and hypopituitarism. Except for some non-neoplastic lesions like sellar abscesses, aneurysms, and dermoid cysts which can have some specific imaging characteristics that can provide clue to pre-operative diagnosis, most of the other neoplastic masses have overlapping radiological features, and pre-operative suspicion remains difficult.
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