ArticleThyroid : official journal of the American Thyroid Association2020
A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials.
Open access · hybridAbstract readMulticenter Study
In one paragraph
Article in Thyroid : official journal of the American Thyroid Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- 2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.European thyroid journal · 2023Guideline
- ThyroidPrint: Thyroid Genetic Classifier Long-Term Follow-Up of Benign Called Lesions.Clinical endocrinology · 2026Article
- Risk of malignancy and necessity of completion thyroidectomy in patients with indeterminate thyroid nodules (Bethesda III and IV), more than expected in endemic region.Updates in surgery · 2026Article
- The actual and future role of molecular tests in thyroid pathology.Virchows Archiv : an international journal of pathology · 2026Review
- Comparing the diagnostic accuracy of pre-operative genetic testing for thyroid cancer on fine needle aspiration cytology specimens: a systematic review and meta-analysis of diagnostic accuracy.Discover oncology · 2025Article
- Molecular Diagnostics and Personalized Therapeutics in Differentiated Thyroid Carcinoma: A Clinically Oriented Review.Diagnostics (Basel, Switzerland) · 2025Review
- Two Decades of Thyroid Nodule Cytology in Children: Malignancy Risk Assessment at a Tertiary Care Center.Hormone research in paediatrics · 2025Article
- Assessment of the risk of malignancy in Bethesda III thyroid nodules: a comprehensive review.Endocrine · 2024Review
- Prediction of the Aggressive Clinical Course of Papillary Thyroid Carcinoma Based on Fine Needle Aspiration Biopsy Molecular Testing.International journal of molecular sciences · 2024Article
- Biomarkers in Thyroid Cancer: Emerging Opportunities from Non-Coding RNAs and Mitochondrial Space.International journal of molecular sciences · 2024Review
- ThyroidPrint®: clinical utility for indeterminate thyroid cytology.Endocrine-related cancer · 2023Article
- Pathogenesis of cancers derived from thyroid follicular cells.Nature reviews. Cancer · 2023Review
- Clinical and histopathological features of follicular thyroid cancer in Chile.Archives of endocrinology and metabolism · 2023Article
- Molecular testing and thyroid nodule management in North America.Gland surgery · 2020Review
- Prognostic Biomarkers for Papillary Thyroid Cancer: Reducing Overtreatment, Improving Clinical Efficiency, and Enhancing Patient Experience.Technology in cancer research & treatmentReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
45 authors at 14 institutions in 2 countries.
Mark ZafereoDepartment of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Bryan McIverDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, Florida, USA.
Sergio Vargas-SalasDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
José Miguel DomínguezDepartment of Endocrinology, Pontificia Universidad Católica de Chile, Santiago, Chile.
David L StewardDepartment of Otolaryngology, Head and Neck Surgery; University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
F Christopher HolsingerDivision of Head and Neck Surgery, Department of Otolaryngology; Palo Alto, California, USA.
Emad KandilDepartment of Surgery, School of Medicine, Tulane University, New Orleans, Louisiana, USA.
Michelle WilliamsDivision of Pathology/Lab Medicine, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Francisco CruzDepartment of Radiology, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Soledad LoyolaDepartment of Radiology, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Antonieta SolarDepartment of Pathology, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Juan Carlos RoaDepartment of Pathology, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Augusto LeónDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Nicolás DroppelmanDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Maite LobosCentro Diagnostico Plaza Italia, Santiago, Chile.
Tatiana AriasClinica UC San Carlos, Santiago, Chile.
Christina S KongDepartment of Pathology; Stanford University, Palo Alto, California, USA.
Naifa BusaidyDepartment of Endocrine Neoplasia, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Elizabeth G GrubbsDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Paul GrahamDepartment of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
John StewartDivision of Pathology/Lab Medicine, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Alice TangDepartment of Otolaryngology, Head and Neck Surgery; University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Jiang WangDepartment of Pathology; University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
Lisa OrloffDivision of Head and Neck Surgery, Department of Otolaryngology; Palo Alto, California, USA.
Marcela HenríquezDepartment of Laboratory Medicine, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Marcela LagosDepartment of Laboratory Medicine, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Miren OsorioClinica Santa Maria Santiago de Chile; Universidad de Chile, Santiago, Chile.
Dina SchachterClinica Santa Maria Santiago de Chile; Universidad de Chile, Santiago, Chile.
Carmen FrancoClinica Santa Maria Santiago de Chile; Universidad de Chile, Santiago, Chile.
Francisco MedinaClinica Santa Maria Santiago de Chile; Universidad de Chile, Santiago, Chile.
Nelson WohllkHospital del Salvador; Universidad de Chile, Santiago, Chile.
René E DiazHospital del Salvador; Universidad de Chile, Santiago, Chile.
Jesús VelizHospital del Salvador; Universidad de Chile, Santiago, Chile.
Eleonora HorvathClínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Hernán TalaClínica Alemana de Santiago, Universidad del Desarrollo, Santiago, Chile.
Pedro PinedaHospital Clínico Universidad de Chile, Santiago, Chile.
Patricia ArroyoHospital San Juan de Dios, Santiago, Chile.
Félix VasquezHospital San Juan de Dios, Santiago, Chile.
Eufrosina TraipeInstituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.
Luis MarínInstituto Oncológico Fundación Arturo López Pérez, Santiago, Chile.
Giovanna MirandaDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Elsa BruceDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Milagros BracamonteDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Natalia MenaDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Hernán E GonzálezDepartment of Surgical Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.
Pontificia Universidad Católica de Chile · CLThe University of Texas MD Anderson Cancer Center · USClinica Santa Maria · CLHospital del Salvador · CLUniversity of Cincinnati · USFundación Arturo López Pérez · CLHospital San Juan de Dios · CLPalo Alto Institute · USUniversidad del Desarrollo · CLCentro de Estudios Científicos · CLHospital Clínico de la Universidad de Chile · CLMoffitt Cancer Center · USPalo Alto University · USTulane University · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdolescentAdultAgedAged, 80 and overBiopsy, Fine-NeedleCytodiagnosisFemaleHumansMaleMiddle AgedProspective StudiesSensitivity and SpecificityThyroid GlandThyroid NeoplasmsThyroid NoduleYoung Adultclinical validationgene classifierindeterminate thyroid cytology
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.