Evidence map›Paper›PMID 31909831›Full record

ArticleImmunology2020

CD8α

Wei Zhang, Li Xu, Xiaoyan Zhang, Jianqing Xu, Jun-O Jin

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Antigen specific activation of cytotoxic CD8Frontiers in cellular and infection microbiology · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Wei ZhangShanghai Public Health Clinical Center &, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-9262-849X
Li XuShanghai Public Health Clinical Center &, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-7883-0448
Xiaoyan ZhangShanghai Public Health Clinical Center &, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-3193-1401
Jianqing XuShanghai Public Health Clinical Center &, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.ORCID 0000-0003-0896-9273
Jun-O JinShanghai Public Health Clinical Center &, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.ORCID 0000-0003-4216-8111
Shanghai Public Health Clinical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are potent immune cells that control innate and adaptive immune responses. Previous studies have shown that the DCs are required for protection against Staphylococcus aureus infection. However, the role of conventional DC (cDC) subsets during S. aureus infection in vivo has not been well investigated. In this study, we examined the function of spleen DC subsets in the activation of immunity against S. aureus infection. C57BL/6 mice were infected intravenously with S. aureus and DC and T-cell activation were analyzed in vivo. We found that the spleen CD8α

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8 AntigensCD8-Positive T-LymphocytesCell LineageDendritic CellsGene ExpressionHost-Pathogen InteractionsImmunity, CellularInterferon-gammaInterleukin-17Lymphocyte ActivationMiceMice, Inbred C57BLPhagocytosisReceptors, Antigen, T-Cell, alpha-betaCD8 antigen, alpha chainCD8 AntigensIl17a protein, mouseInterferon-gammaInterleukin-17Receptors, Antigen, T-Cell, alpha-betaCD8α− dendritic cellsinterferon-γinterleukin-17Staphylococcus aureusVβ T cells

Identifiers

PMID31909831
PMCPMC7077999
OpenAlexW3000061828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.