Evidence map›Paper›PMID 31909711›Full record

ArticleeLife2020

The genetic basis of aneuploidy tolerance in wild yeast.

James Hose, Leah E Escalante, Katie J Clowers, H Auguste Dutcher, DeElegant Robinson, Venera Bouriakov, Joshua J Coon, Evgenia Shishkova, Audrey P Gasch

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 92 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

James HoseCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Leah E EscalanteCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Katie J ClowersLaboratory of Genetics, University of Wisconsin-Madison, Madison, United States.
H Auguste DutcherCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
DeElegant RobinsonCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Venera BouriakovCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Joshua J CoonCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Evgenia ShishkovaCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.
Audrey P GaschCenter for Genomic Science Innovation, University of Wisconsin-Madison, Madison, United States.ORCID 0000-0002-8182-257X
University of Wisconsin–Madison · US

Funding

Institutional Training in the Genomic SciencesT32HG002760 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI Qiongshi Lu · 2003 to 2026
$17.7M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
TR&D 2 Metabolic Labels for Ultraplexed Protein Quantification p. 453P41GM108538 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COON, JOSHUA J · 2016 to 2025
$13.1M
Molecular approaches to sensitizing eukaryotic cells to aneuploidyR01CA229532 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI GASCH, AUDREY · 2018 to 2022
$1.8M
NCI NIH HHS R01 CA229532NHGRI NIH HHS T32 HG002760NIGMS NIH HHS P41 GM108538NIGMS NIH HHS T32 GM007133NIH HHS T32 HG002760U.S. Department of Energy DE-SC0018409
6 · The paper itself

Abstract

Aneuploidy is highly detrimental during development yet common in cancers and pathogenic fungi - what gives rise to differences in aneuploidy tolerance remains unclear. We previously showed that wild isolates of

Indexed as

AneuploidySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSaccharomyces cerevisiae ProteinsSsd1 protein, S cerevisiaeaneuploidychromosomesgene expressionnatural variationproteotoxicityS. cerevisiaewild strains

Identifiers

PMID31909711
PMCPMC6970514
OpenAlexW2999000740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.