Evidence map›Paper›PMID 31909710›Full record

ArticleeLife2020

Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry.

Samuel G Usher, Frances M Ashcroft, Michael C Puljung

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. A Historical Outline of Fluorescence Spectroscopy in Ion Channel Research.Advances in experimental medicine and biology · 2026
    Review
  2. Measuring serotonin binding to its receptorsbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. A fluorescent probe for the enzymatic activity of KbioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Dynamic duo: Kir6 and SUR in KChannels (Austin, Tex.) · 2024
    Review
  8. Review
  9. Structure of an open KNature communications · 2024
    Article
  10. Review
  11. KCurrent opinion in structural biology · 2023
    Review
  12. Review
  13. Article
  14. The dynamic interplay of PIPThe Journal of physiology · 2022
    Article
  15. Functional Regulation of KFrontiers in pharmacology · 2022
    Review
  16. Molecular structure of an open human KProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Samuel G UsherDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2487-6547
Frances M AshcroftDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-6970-1767
Michael C PuljungDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-9335-0936
University of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R002517/1Wellcome 203731/Z/16/AWellcome Trust
6 · The paper itself

Abstract

Pancreatic ATP-sensitive K

Indexed as

FluorometryPatch-Clamp TechniquesG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHEK293 CellsHumansKcnj11 ChannelPancreasPotassium Channels, Inwardly RectifyingSulfonylurea ReceptorsABCC8 protein, humanG Protein-Coupled Inwardly-Rectifying Potassium ChannelsKcnj11 ChannelKCNJ5 protein, humanPotassium Channels, Inwardly RectifyingSulfonylurea Receptorsallosterychannel gatingdiabetesion channelligand bindingmetabolismmolecular biophysicsnonestructural biology

Identifiers

PMID31909710
PMCPMC7004565
OpenAlexW2999013415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.