Evidence map›Paper›PMID 31909700›Full record

ArticleRadiology2020

The QIBA Profile for FDG PET/CT as an Imaging Biomarker Measuring Response to Cancer Therapy.

Paul E Kinahan, Eric S Perlman, John J Sunderland, Rathan Subramaniam, Scott D Wollenweber, Timothy G Turkington, Martin A Lodge, Ronald Boellaard, Nancy A Obuchowski, Richard L Wahl

Abstract read
In one paragraph

Article in Radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Correlation of FAPI PET Uptake with Immunohistochemistry in Explanted Lungs from Patients with Advanced Interstitial Lung Disease.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Trial
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  12. A compositeBreast (Edinburgh, Scotland) · 2025
    Article
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  16. Review
  17. [Asia Oceania journal of nuclear medicine & biology · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Paul E KinahanFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0001-6461-3306
Eric S PerlmanFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).
John J SunderlandFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).
Rathan SubramaniamFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0001-9417-0649
Scott D WollenweberFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0001-6105-6831
Timothy G TurkingtonFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0003-0091-4681
Martin A LodgeFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0003-0922-6519
Ronald BoellaardFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0002-0313-5686
Nancy A ObuchowskiFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0003-1891-7477
Richard L WahlFrom the Department of Radiology, University of Washington, 1959 NE Pacific St, RR215, Box 357115, Seattle, WA 98195-7117 (P.E.K.); Perlman Advisory Group, LLC, Hillsdale, NY (E.S.P.); Department of Radiology, University of Iowa, Iowa City, Iowa (J.J.S.); Department of Radiology, University of Texas Southwestern, Dallas, Tex (R.S.); GE Healthcare, Waukesha, Wis (S.D.W.); Department of Radiology, Duke University Medical Center, Durham, NC (T.G.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Md (M.A.L.); Department of Radiology and Nuclear Medicine, Amsterdam, the Netherlands (R.B.); Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio (N.A.O.); and Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (R.L.W.).ORCID 0000-0002-7306-2590

Funding

Advanced PET/CT Imaging for Improving Clinical TrialsU01CA148131 · NCI · UNIVERSITY OF WASHINGTON · PI KINAHAN, PAUL E., LINDEN, HANNAH M · 2010 to 2019
$6.0M
ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical TrialsU01CA190254 · NCI · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · PI SCHNALL, MITCHELL D. · 2015 to 2019
$3.2M
Harmonized PET Reconstructions for Cancer Clinical TrialsR01CA169072 · NCI · UNIVERSITY OF IOWA · PI KARP, JOEL S, KINAHAN, PAUL E. · 2012 to 2016
$2.4M
NCI NIH HHS R01 CA169072NCI NIH HHS U01 CA148131NCI NIH HHS U01 CA190254NHLBI NIH HHS HHSN268201500021CNIBIB NIH HHS HHSN268201000050CNIBIB NIH HHS HHSN268201300071C
6 · The paper itself

Abstract

The Quantitative Imaging Biomarkers Alliance (QIBA) Profile for fluorodeoxyglucose (FDG) PET/CT imaging was created by QIBA to both characterize and reduce the variability of standardized uptake values (SUVs). The Profile provides two complementary claims on the precision of SUV measurements. First, tumor glycolytic activity as reflected by the maximum SUV (SUV

Indexed as

Biomarkers, TumorFluorodeoxyglucose F18HumansImage Interpretation, Computer-AssistedNeoplasmsNeoplasm StagingPositron Emission Tomography Computed TomographyTreatment OutcomeBiomarkers, TumorFluorodeoxyglucose F18

Identifiers

PMID31909700
PMCPMC7053216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.