Evidence map›Paper›PMID 31909687›Full record

ArticleBioengineered2020

miR-25-3p inhibition impairs tumorigenesis and invasion in gastric cancer cells

Liang Ning, Maoshen Zhang, Qingli Zhu, Fengyun Hao, Wenlong Shen, Dong Chen

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liang NingDepartment of General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Maoshen ZhangDepartment of General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qingli ZhuDepartment of Thyroid Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Fengyun HaoDepartment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.ORCID 0000-0003-4325-6957
Wenlong ShenDepartment of Anorectal, Qilu Hospital of Shandong University, Qingdao, Shandong, PR China.ORCID 0000-0003-2872-8776
Dong ChenDepartment of General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qingdao University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deregulated expression of microRNAs (miRNAs) plays a role in the pathogenesis and progression of gastric cancer (GC). Among upregulated miRNAs, miR-25-3p has oncogenic potential and therefore represents an attractive target for the treatment of GC. Here, we investigated the role of miR-25-3p on GC cells

Indexed as

AnimalsCarcinogenesisCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMiceMice, Inbred BALB CMice, NudeMice, SCIDMicroRNAsNeoplasm InvasivenessStomach NeoplasmsMicroRNAsMIRN25 microRNA, humanMIRN25 microRNA, mouseGastric cancerInvasionMetastasismicroRNAmiR-25-3pmiR-25 inhibitor

Identifiers

PMID31909687
PMCPMC6961587
OpenAlexW3000087874

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.