Evidence map›Paper›PMID 31909681›Full record

ReviewBioengineered2020

A review on microalgae cultivation and harvesting, and their biomass extraction processing using ionic liquids.

Jia Sen Tan, Sze Ying Lee, Kit Wayne Chew, Man Kee Lam, Jun Wei Lim, Shih-Hsin Ho, Pau Loke Show

RetractedAbstract readReviewRetracted Publication
In one paragraph

Review in Bioengineered, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
  7. Growth ofBioengineering (Basel, Switzerland) · 2025
    Article
  8. Life (Basel, Switzerland) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jia Sen TanDepartment of Biotechnology, Faculty of Applied Science, UCSI University, Kuala Lumpur, Malaysia.
Sze Ying LeeDepartment of Chemical Engineering, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Sungai Long Campus, Kajang, Malaysia.
Kit Wayne ChewSchool of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Selangor, Malaysia.
Man Kee LamChemical Engineering Department, Universiti Teknologi PETRONAS, Perak, Malaysia.
Jun Wei LimCentre for Biofuel and Biochemical Research, Institute of Self-Sustainable Building, Universiti Teknologi PETRONAS, Seri Iskandar, Malaysia.ORCID 0000-0003-0158-8822
Shih-Hsin HoState Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin, China.
Pau Loke ShowDepartment of Chemical and Environmental Engineering, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Malaysia.ORCID 0000-0002-0913-5409

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The richness of high-value bio-compounds derived from microalgae has made microalgae a promising and sustainable source of useful product. The present work starts with a review on the usage of open pond and photobioreactor in culturing various microalgae strains, followed by an in-depth evaluation on the common harvesting techniques used to collect microalgae from culture medium. The harvesting methods discussed include filtration, centrifugation, flocculation, and flotation. Additionally, the advanced extraction technologies using ionic liquids as extractive solvents applied to extract high-value bio-compounds such as lipids, carbohydrates, proteins, and other bioactive compounds from microalgae biomass are summarized and discussed. However, more work needs to be done to fully utilize the potential of microalgae biomass for the application in large-scale production of biofuels, food additives, and nutritive supplements.

Indexed as

BiofuelsBiomassCulture MediaIonic LiquidsMicroalgaePlant ExtractsBiofuelsCulture MediaIonic LiquidsPlant Extractscultivationdownstream processingextractionharvestingionic liquidsMicroalgae

Identifiers

PMID31909681
PMCPMC6999644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.