Evidence map›Paper›PMID 31909595›Full record

ArticleBioconjugate chemistry2020

Role of Albumin in Accumulation and Persistence of Tumor-Seeking Cyanine Dyes.

Syed Muhammad Usama, G Kate Park, Shinsuke Nomura, Yoonji Baek, Hak Soo Choi, Kevin Burgess

Open access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Pooled it
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  14. Unveiling role of serum albumin in disaggregation and cellular delivery of a near-infrared chlorophyll-based photosensitizer in breast cancer cells.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Syed Muhammad UsamaDepartment of Chemistry , Texas A & M University , College Station , Texas 77842 , United States.ORCID 0000-0002-7487-1568
G Kate ParkGordon Center for Medical Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
Shinsuke NomuraGordon Center for Medical Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
Yoonji BaekGordon Center for Medical Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.
Hak Soo ChoiGordon Center for Medical Imaging, Department of Radiology , Massachusetts General Hospital and Harvard Medical School , Boston , Massachusetts 02114 , United States.ORCID 0000-0002-7982-6483
Kevin BurgessDepartment of Chemistry , Texas A & M University , College Station , Texas 77842 , United States.ORCID 0000-0001-6597-1842
Harvard University · USTexas A&M University · US

Funding

OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
Image-Guided Drug Delivery for Pancreatic Neuroendocrine Tumor.R01EB022230 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, HAK SOO, HENARY, MAGED M · 2017 to 2020
$3.6M
Nanochelation Therapies for Iron Overload DisordersR01HL143020 · NHLBI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CHOI, HAK SOO, KIM, JONGHAN · 2018 to 2021
$2.6M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
Image-Guided Drug Delivery and Treatment for GISTR21CA223270 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CHOI, HAK SOO · 2018 to 2019
$398k
NCI NIH HHS R21 CA223270NEI NIH HHS R01 EY024544NHLBI NIH HHS R01 HL143020NIBIB NIH HHS R01 EB022230NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

Some heptamethine cyanine dyes accumulate in solid tumors

Indexed as

AlbuminsAnimalsCarbocyaninesCell Line, TumorFluorescent DyesHep G2 CellsHumansIndolesMice, Inbred C57BLNeoplasmsOptical ImagingOrganic Anion TransportersAlbuminsCarbocyaninesFluorescent DyesIndolesMHI-148Organic Anion Transporters

Identifiers

PMID31909595
PMCPMC7174984
OpenAlexW3000241374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.