Evidence map›Paper›PMID 31909541›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

Deficiency of immunoglobulin E protects mice from experimental abdominal aortic aneurysms.

Jie Li, Zhiyong Deng, Xian Zhang, Feng Liu, Chongzhe Yang, Guo-Ping Shi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jie LiDepartment of Geriatrics, National Key Clinic Specialty, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Zhiyong DengDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Xian ZhangDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Feng LiuDepartment of Geriatrics, National Key Clinic Specialty, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Chongzhe YangDepartment of Geriatrics, National Key Clinic Specialty, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Guo-Ping ShiDepartment of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Harvard University · USGuangzhou First People's Hospital · CNSouth China University of Technology · CN

Funding

Role of mast cells in obesityR01HL060942 · NHLBI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI SHI, GUO-PING · 1999 to 2019
$5.6M
Role of a novel IL18 binding protein in atherosclerosisR01HL123568 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SHI, GUO-PING · 2015 to 2018
$1.7M
Role of mast cells in Alzheimer's DiseaseR56AG058670 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHI, GUO-PING · 2018 to 2018
$415k
Fundamental Research Funds for the Central Universities, SCUT D2180650NHLBI NIH HHS R01 HL060942NHLBI NIH HHS R01 HL123568NIA NIH HHS R56 AG058670
6 · The paper itself

Abstract

Allergic asthma with high plasma IgE levels is a significant risk factor of human abdominal aortic aneurysm (AAA). This study tests a direct role of IgE in angiotensin-II (Ang-II) perfusion- and peri-aortic CaCl

Indexed as

AnimalsAortic Aneurysm, AbdominalCalcium ChlorideChemokine CXCL2Immunoglobulin EInterleukin-6MiceMice, Knockout, ApoENeutrophilsReceptors, IgECalcium ChlorideChemokine CXCL2Immunoglobulin EInterleukin-6interleukin-6, mouseReceptors, IgEabdominal aortic aneurysmFcεR1IgEIL6MAPKneutrophil

Identifiers

PMID31909541
PMCPMC7018578
OpenAlexW2998155039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.