Evidence map›Paper›PMID 31909504›Full record

ReviewHepatology (Baltimore, Md.)2020

Liver-on-a-Chip Models of Fatty Liver Disease.

Shabir Hassan, Shikha Sebastian, Sushila Maharjan, Ami Lesha, Anne-Marie Carpenter, Xiuli Liu, Xin Xie, Carol Livermore, Yu Shrike Zhang, Ali Zarrinpar

Open access · greenAbstract readReview
In one paragraph

Review in Hepatology (Baltimore, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 113 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Lessons Learned from Liver-on-Chip Platform.Annals of biomedical engineering · 2025
    Review
  12. Review
  13. Review
  14. Functional Liver Cell-Based Platforms in Biomedical Research.Pharmacology research & perspectives · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shabir HassanDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Shikha SebastianDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Sushila MaharjanDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Ami LeshaDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Anne-Marie CarpenterDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL.
Xiuli LiuDepartment of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.
Xin XieDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Carol LivermoreMicropower and Nanoengineering Lab, Department of Mechanical and Industrial Engineering, Northeastern University, Boston, MA.
Yu Shrike ZhangDivision of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA.
Ali ZarrinparDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL.ORCID 0000-0002-6812-1816
Brigham and Women's Hospital · USUniversity of Florida · USNortheastern University · US

Funding

High-Throughput Volumetric Photoacoustic Imaging of Living Vascularized OrganoidsR01EB028143 · NIBIB · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2022
$2.0M
Ischemia-reperfusion injury in liver transplantationK08DK113244 · NIDDK · UNIVERSITY OF FLORIDA · PI ZARRINPAR, ALI · 2017 to 2021
$814k
Recapitulating Ductal Carcinoma on a Chip for Personalized Breast Cancer TherapyR00CA201603 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHANG, Y. SHRIKE · 2019 to 2021
$747k
Multiscale Stereolithogrphic Bioprinting of Stage-Matching Vascularized Tumor ModelsR21EB025270 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI ZHANG, Y. SHRIKE · 2018 to 2020
$726k
NCI NIH HHS R00CA201603NIBIB NIH HHS R01EB028143NIBIB NIH HHS R21EB025270NIDDK NIH HHS K08 DK113244
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fatty LiverLab-On-A-Chip DevicesHumansModels, Structural

Identifiers

PMID31909504
PMCPMC7012755
OpenAlexW2999601492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.