Evidence map›Paper›PMID 31909353›Full record

ArticleHepatology communications2020

Self-Renewal Capability of Hepatocytic Parental Progenitor Cells Derived From Adult Rat Liver Is Maintained Long Term When Cultured on Laminin 111 in Serum-Free Medium.

Junichi Kino, Norihisa Ichinohe, Masayuki Ishii, Hiromu Suzuki, Toru Mizuguchi, Naoki Tanimizu, Toshihiro Mitaka

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Junichi KinoDepartment of Tissue Development and Regeneration Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Sapporo Japan.
Norihisa IchinoheDepartment of Tissue Development and Regeneration Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Sapporo Japan.
Masayuki IshiiDepartment of Tissue Development and Regeneration Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Sapporo Japan.
Hiromu SuzukiDepartment of Molecular Biology Sapporo Medical University School of Medicine Sapporo Japan.
Toru MizuguchiDepartment of Surgery Surgical Oncology and Science Sapporo Medical University School of Medicine Sapporo Japan.
Naoki TanimizuDepartment of Tissue Development and Regeneration Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Sapporo Japan.
Toshihiro MitakaDepartment of Tissue Development and Regeneration Research Institute for Frontier Medicine Sapporo Medical University School of Medicine Sapporo Japan.ORCID https://orcid.org/0000-0001-9467-4871
Sapporo Medical University · JPOtsuka (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated how the ability of hepatocytic parental progenitor cells (HPPCs) to self-renew can be maintained and how laminin (LN) isoforms play an important role in their self-renewal and maturation. Hepatocytes isolated from adult rat livers were cultured on hyaluronic acid to form colonies consisting of CD44

Identifiers

PMID31909353
PMCPMC6939498
OpenAlexW2983442686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.