Evidence map›Paper›PMID 31909291›Full record

ArticleContemporary clinical trials communications2020

Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness.

Nicola Metrebian, Timothy Weaver, Stephen Pilling, Kimberley Goldsmith, Ewan Carr, James Shearer, Kathryn Woolston-Thomas, Basak Tas, Carol-Ann Getty, Charlotte Cooper and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Contingency Management for Drug Use Disorders: Meta-Analysis and Application of Tolin's Criteria.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Nicola MetrebianKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Timothy WeaverMiddlesex University, Department of Mental Health, Social Work and Integrative Medicine, School of Health and Education, The Burroughs, London, NW4 4BT, UK.
Stephen PillingUniversity College London, National Collaborating Centre for Mental Health, Research Department of Clinical, Educational and Health Psychology, University College London 1-19 Torrington Place London, WC1 7HB, UK.
Kimberley GoldsmithKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Ewan CarrKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
James ShearerKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Kathryn Woolston-ThomasKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Basak TasKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Carol-Ann GettyKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Charlotte CooperKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Rob van der WaalSouth London and Maudsley NHS Foundation Trust, Southwark, Central Acute and Addictions Directorate, Marina House, 63-65 Denmark Hill, London, SE5 8RS, UK.
Michael KelleherSouth London and Maudsley NHS Foundation Trust, Southwark, Central Acute and Addictions Directorate, Marina House, 63-65 Denmark Hill, London, SE5 8RS, UK.
Emily FinchSouth London and Maudsley NHS Foundation Trust, Southwark, Central Acute and Addictions Directorate, Marina House, 63-65 Denmark Hill, London, SE5 8RS, UK.
Prun BijralChange, Grow, Live, 39-41 Thomas Street, Manchester, M4 1NA, UK.
David TaylorKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
Jenny ScottUniversity of Bath, Claverton Down, Bath, BA2 7AY, UK.
John StrangKing's College London, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, Camberwell, London, SE5 8AB, UK.
King's College London · GBSouth London and Maudsley NHS Foundation Trust · GBCentre for Mental Health · GBMiddlesex University · GBUniversity of Bath · GB

Funding

Department of Health PB-PG-0815-20053
6 · The paper itself

Abstract

The majority of people receiving treatment for their heroin addiction, are prescribed methadone; for which there is an extensive evidence base. When treatment starts, people take their daily dose of methadone under supervision at a community pharmacy. Supervision guarantees methadone is taken as directed by the individual for whom it has been prescribed, helps to ensure individuals take their correct dose every day, and safeguards against diversion and overdose. However, individuals often fail to attend the pharmacy to take their methadone. Each missed dose is of concern. If a patient misses their daily dose of methadone, they will start to experience opiate withdrawal and cravings and are more likely to use heroin. If they miss three days dose, there are concerns that they may lose tolerance to the drug and may be at risk of overdose when the next dose is taken. Hence there is an urgent need to develop effective interventions for medication adherence. Research suggests that incentive-based medication adherence interventions may be very effective, but there are few controlled trials and the provision of incentives requires time and organisational systems which can be challenging in pharmacies. The investigators have developed the technology to deliver incentives by mobile telephone. This cluster randomised trial will test the feasibility of conducting a future trial evaluating the clinical and cost effectiveness of using telephone delivered incentives (praise and modest financial rewards via text messaging) to encourage adherence with supervised consumption of methadone in community pharmacies. Three drug services (each with two or three community pharmacies supervising methadone consumption that will enrol 20 individuals, a total of 60 participants) will be recruited and randomly allocated to deliver either i) telephone delivered incentives, ii) telephone delivered reminders or iii) no telephone system. Acceptability, recruitment, follow-up, and suitable measures of clinical and cost effectiveness will be assessed. Findings from this feasibility study will be assessed against stated progression criteria and used to inform a future confirmatory trial of the clinical and cost effectiveness of telephone delivered incentives to encourage medication adherence.

trial registrationISRCTN58958179 (retrospectively registered).

Indexed as

Behavioural reinforcementContingency managementFinancial incentivesHeroin useMedication adherenceMethadoneOpiate substitution treatmentPharmaciesSupervised consumption

Identifiers

PMID31909291
PMCPMC6938936
OpenAlexW2994819133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.