Evidence map›Paper›PMID 31909147›Full record

ArticlePractical laboratory medicine2020

Evaluation of a semi-automatic isoelectric focusing method for apolipoprotein E phenotyping.

Randa Bittar, Alain Carrié, Georges Nouadje, Corinne Cherfils, Valérie Fesel-Fouquier, Laurence Barbot-Trystram, Philippe Giral, Dominique Bonnefont-Rousselot

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Practical laboratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Randa BittarService de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
Alain CarriéSorbonne Université, UMR_S1166 ICAN, F-75013, Paris, France.
Georges NouadjeSebia, F-91008, Evry, France.
Corinne CherfilsService de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
Valérie Fesel-FouquierService de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
Laurence Barbot-TrystramService de Coprologie Fonctionnelle, AP-HP.Sorbonne Université, F-75013, Paris, France.
Philippe GiralSorbonne Université, UMR_S1166 ICAN, F-75013, Paris, France.
Dominique Bonnefont-RousselotService de Biochimie Métabolique, AP-HP.Sorbonne Université, F-75013, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRSorbonne Université · FRCentre National de la Recherche Scientifique · FRSebia (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A qualitative, semi-automatized method for apolipoprotein E (apoE) phenotyping by isoelectric focusing method has been evaluated on 40 serum samples from patients previously genotyped for apoE, especially as regards concordance with genotyping, but also repeatability and reproducibility of the method, and sample storage. Total concordance with genotyping and good precision criteria, together with its practicability and requirement of a little sample volume, lead to conclude to the usefulness of this method to help clinicians in the diagnosis of dyslipidemic and neurodegenerative diseases.

Indexed as

apo, apolipoproteinApolipoprotein EHDL, high density lipoproteinIDL, intermediate density lipoproteinIEF, isoelectric focusingIsoelectric focusingIsoformsLDL, low density lipoproteinPhenotypeVLDL, very low density lipoprotein

Identifiers

PMID31909147
PMCPMC6939034
OpenAlexW2996350747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.