Evidence map›Paper›PMID 31909125›Full record

ArticleData in brief2020

Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus.

A L Rusanov, A A Stepanov, V G Zgoda, A L Kaysheva, M Selinger, H Maskova, D Loginov, J Sterba, L Grubhoffer, N G Luzgina

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Proteome Profiling of PMJ2-R and Primary Peritoneal Macrophages.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

A L RusanovV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
A A StepanovV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
V G ZgodaV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
A L KayshevaV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
M SelingerFaculty of Science, University of South Bohemia, Branišovská 1760, 37005, České Budějovice, Czech Republic.
H MaskovaFaculty of Science, University of South Bohemia, Branišovská 1760, 37005, České Budějovice, Czech Republic.
D LoginovV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
J SterbaFaculty of Science, University of South Bohemia, Branišovská 1760, 37005, České Budějovice, Czech Republic.
L GrubhofferFaculty of Science, University of South Bohemia, Branišovská 1760, 37005, České Budějovice, Czech Republic.
N G LuzginaV. N. Orehovich Institute of Biomedical Chemistry, Russian Federation.
Institute of Biomedical Chemistry · RUUniversity of South Bohemia in České Budějovice · CZCzech Academy of Sciences, Biology Centre · CZInstitute of Parasitology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the proteomic datasets on the mouse macrophage cell line PMJ2R infected with tick-borne encephalitis virus (TBEV) for two and six days. Data were acquired using shotgun ultra-high resolution mass spectrometry. Peptide identifications were done using the Mascot version 2.4 (Matrix Science), and quantification was performed by a label-free approach. Protein profiles of early (two days) and late (six days) stages of infection were compared between each other and the respective control samples. Protein profiles of infected and control samples differed in the number of identified proteins and their relative abundances. Proteins detected in the TBEV-infected cells were involved in various processes related to the infection, including defense response against the virus, regulation of viral process, negative regulation of viral genome replication, RNA binding, or innate immune response. Also, proteins specific for the early and late stages of infection were identified.

Indexed as

Label-free quantificationMass spectrometryMouse macrophage cell lineProteinProteomicsTBEV

Identifiers

PMID31909125
PMCPMC6939094
OpenAlexW2995314208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.