Evidence map›Paper›PMID 31908930›Full record

ArticleJournal of orthopaedic translation2020

Design of a new magnesium-based anterior cruciate ligament interference screw using finite element analysis.

Jonquil R Mau, Kevin M Hawkins, Savio L-Y Woo, Kwang E Kim, Matthew B A McCullough

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Article in Journal of orthopaedic translation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonquil R MauDepartment of Chemical, Biological, and Bioengineering, North Carolina A&T State University, Greensboro, NC, USA.
Kevin M HawkinsDepartment of Chemical, Biological, and Bioengineering, North Carolina A&T State University, Greensboro, NC, USA.
Savio L-Y WooMusculoskeletal Research Center, Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Kwang E KimMusculoskeletal Research Center, Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Matthew B A McCulloughDepartment of Chemical, Biological, and Bioengineering, North Carolina A&T State University, Greensboro, NC, USA.

Funding

Training in Biomechanics in Regenerative MedicineT32EB003392 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WOO, SAVIO L-Y. · 2005 to 2020
$4.0M
NIBIB NIH HHS T32 EB003392
6 · The paper itself

Abstract

BACKGROUND/

objectiveIn anterior cruciate ligament ​reconstruction, a tendon graft, anchored by interference screws (IFSs), is frequently used as a replacement for the damaged ligament. Generally, IFSs are classified as being either metallic or polymeric. Metallic screws have sharp threads that lacerate the graft, preventing solid fixation. These constructs are difficult to image ​and can limit bone--screw integration because of the higher stiffness of the screw. Polymeric materials are often a better match to bone's material properties, but lack the strength needed to hold grafts in place. Magnesium (Mg) is a material of great promise for orthopaedic applications. Mg has mechanical properties similar to bone, ability to be seen on magnetic resonance imagings, and promotes bone healing. However, questions still remain regarding the strength of Mg-based screws. Previous

methodsUsing finite element analysis, a comparison study of six drive designs (hexagonal, quadrangle, torx, trigonal, trilobe, and turbine) was performed. This was followed by a parametric analysis to determine appropriate drive depth and drive width.

resultsIt was observed that with a typical torque (2 ​Nm) used for screw insertion during anterior cruciate ligament reconstruction, the maximum von Mises and shear stress values were concentrated in the corners or turns of the drive, which could lead to stripping if the values were greater than the yield stress of Mg (193 ​MPa). With a four-time ​increase in drive depth to be fully driven and a 30% greater drive width, these maximum stress values were significantly decreased by more than 75%.

conclusionIt was concluded that improving the design of a Mg-based screw may increase surgical success rates, by decreasing device failure at insertion. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: The results of this work have the potential to improve designs of degradable IFSs, allowing for greater torque to be applied and thus greater screw fixation between host bone and the graft. Such a fixation will allow greater integration, better patient healing, and ultimately improved patient outcomes.

Indexed as

Finite element analysisInterference screwScrew designScrew insertion

Identifiers

PMID31908930
PMCPMC6939101

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