Evidence map›Paper›PMID 31908831›Full record

ArticleNPJ biofilms and microbiomes2020

Metal ions weaken the hydrophobicity and antibiotic resistance of

Carolina Falcón García, Martin Kretschmer, Carlos N Lozano-Andrade, Markus Schönleitner, Anna Dragoŝ, Ákos T Kovács, Oliver Lieleg

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  4. ZnO Nanocrystals InhibitInternational journal of nanomedicine · 2026
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  5. Animals : an open access journal from MDPI · 2025
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  6. Antibiotic resistance and pathogenicity of Shiga-toxin-producingJournal of advanced veterinary and animal research · 2025
    Article
  7. Lanthanide bioadsorption by the extremophileFrontiers in microbiology · 2025
    Article
  8. Strain-SpecificInternational journal of nanomedicine · 2025
    Article
  9. Article
  10. Taxonomy ofmSystems · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Identification ofPathogens (Basel, Switzerland) · 2021
    Article
  16. Review
  17. Article
  18. Re-sensitizing Ampicillin and Kanamycin-ResistantFrontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolina Falcón García1Department of Mechanical Engineering and Munich School of Bioengineering, Technical University of Munich, Boltzmannstraße 11, 85748 Garching, Germany.ORCID 0000-0003-0228-8661
Martin Kretschmer1Department of Mechanical Engineering and Munich School of Bioengineering, Technical University of Munich, Boltzmannstraße 11, 85748 Garching, Germany.
Carlos N Lozano-Andrade2Bacterial Interactions and Evolution Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0003-2805-4505
Markus Schönleitner1Department of Mechanical Engineering and Munich School of Bioengineering, Technical University of Munich, Boltzmannstraße 11, 85748 Garching, Germany.ORCID 0000-0003-3767-2858
Anna Dragoŝ2Bacterial Interactions and Evolution Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 221, 2800 Kongens Lyngby, Denmark.
Ákos T Kovács2Bacterial Interactions and Evolution Group, Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-4465-1636
Oliver Lieleg1Department of Mechanical Engineering and Munich School of Bioengineering, Technical University of Munich, Boltzmannstraße 11, 85748 Garching, Germany.ORCID 0000-0002-6874-7456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface superhydrophobicity makes bacterial biofilms very difficult to fight, and it is a combination of their matrix composition and complex surface roughness which synergistically protects these biomaterials from wetting. Although trying to eradicate biofilms with aqueous (antibiotic) solutions is common practice, this can be a futile approach if the biofilms have superhydrophobic properties. To date, there are not many options available to reduce the liquid repellency of biofilms or to prevent this material property from developing. Here, we present a solution to this challenge. We demonstrate how the addition of metal ions such as copper and zinc during or after biofilm formation can render the surface of otherwise superhydrophobic

Indexed as

Bacillus subtilisBiofilmsCopperDrug Resistance, MicrobialHydrophobic and Hydrophilic InteractionsMetalsSurface PropertiesWettabilityZincCopperMetalsZincAntimicrobialsBiofilmsBioremediation

Identifiers

PMID31908831
PMCPMC6941983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.