ArticleBMJ open diabetes research & care2019
Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study.
Article in BMJ open diabetes research & care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis.BMJ open diabetes research & care · 2024Pooled it
- Ethnic differences between South Asians and White Caucasians in cardiovascular disease-related mortality in developed countries: a systematic literature review.Systematic reviews · 2022Pooled it
- Differential Pathophysiological Drivers of Susceptibility to Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease: Ethnic Differences in Insulin Dynamics, Whole-Body Fat Metabolism, and Organ-Specific Lipid Deposition.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Ethnic differences in the burden of cardiovascular disease risk factors among adult residents of London: the TOGETHER study.BMC medicine · 2026Article
- HDL protein composition differs between young white European and South Asian men before and after weight gain.Clinical science (London, England : 1979) · 2025Article
- Ectopic Fat distribution and adverse muscle composition in South Asians: Findings from the UK biobank.American journal of preventive cardiology · 2025Article
- A Mendelian randomization study of type 2 diabetes and cancer risk in East Asians.Cancer cell international · 2025Article
- The effect of acute hot water immersion on cutaneous peripheral microvascular responses in males of White-European, Black-African and South-Asian descent.Temperature (Austin, Tex.) · 2025Article
- Evidence of gene-nutrient interaction association with waist circumference, cross-sectional analysis.BMC public health · 2024Article
- Incident Cancer Risk of Patients with Prevalent Type 2 Diabetes Mellitus in Hungary (Part 2).Cancers · 2024Article
- Lipoprotein Insulin Resistance Index: A Simple, Accurate Method for Assessing Insulin Resistance in South Asians.Journal of the Endocrine Society · 2023Article
- EVOO's Effects on Incretin Production: Is There a Rationale for a Combination in T2DM Therapy?International journal of molecular sciences · 2022Review
- Triglyceride glucose index exacerbates the risk of future cardiovascular disease due to diabetes: evidence from the China Health and Retirement Longitudinal Survey (CHARLS).BMC cardiovascular disorders · 2022Article
- Ethnic differences in cardiovascular risk: examining differential exposure and susceptibility to risk factors.BMC medicine · 2022Article
- Article
- Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study.BMJ open diabetes research & care · 2021Article
- Heterogeneity amongst GLP-1 RA cardiovascular outcome trials results: can definition of established cardiovascular disease be the missing link?Diabetology & metabolic syndrome · 2021Review
- Association of Hypertension and Diabetes with Ischemic Heart Disease and Stroke Mortality in India: The Million Death Study.Global heart · 2021Article
- Utilizing diabetes registry for exploring sociodemographic and clinical characteristics of type II diabetic patients in Saudi Arabia.Saudi medical journal · 2021Article
- Association of sleep disturbance with risk of cardiovascular disease and all-cause mortality in patients with new-onset type 2 diabetes: data from the Korean NHIS-HEALS.Cardiovascular diabetology · 2020Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 3 countries.
Funding
Abstract
Objective: To investigate whether the health implications of having type 2 diabetes (T2D) were different in South Asian compared with white European participants. Research design and methods: Prospective data from UK Biobank were used, and 457 935 participants of white European and 7102 of South Asian background were included. Cox proportional regression was performed to investigate the association between T2D and health outcome by ethnicity. Results: Over a mean of 7.0 years (IQR 6.3-7.6) of follow-up, 12 974 participants had died, and 30 347 and 27 159 developed cardiovascular disease (CVD) and cancer, respectively. South Asians had a higher risk for CVD mortality (HR: 1.42, 95% CI 1.07 to 1.89) and incidence (HR: 1.78, 95% CI 1.63 to 1.94), but a decreased risk for cancer mortality (HR: 0.59, 95% CI 0.41 to 0.85) and incidence (HR: 0.80, 95% CI 0.70 to 0.92) compared with white Europeans. Compared with individuals without T2D, both white Europeans and South Asians with T2D had a higher risk for all-cause mortality (1.59 (1.48 to 1.71) vs 2.83 (1.76 to 4.53)), CVD mortality (2.04 (1.82 to 2.28) vs 4.40 (2.37 to 8.16)) and CVD incidence (1.37 (1.31 to 1.44) vs 1.60 (1.31 to 1.95)), respectively. However, the magnitude of the risk was higher for South Asians than white Europeans. Conclusions: Although T2D was associated with a higher risk for all-cause mortality and CVD incidence and mortality, in both white Europeans and South Asians, the risk experienced by South Asians with T2D was higher than their white European counterparts.
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