Evidence map›Paper›PMID 31908791›Full record

ArticleBMJ open diabetes research & care2019

Patterns of postmeal insulin secretion in individuals with sulfonylurea-treated

Pamela Bowman, Timothy J McDonald, Bridget A Knight, Sarah E Flanagan, Maria Leveridge, Steve R Spaull, Beverley M Shields, Suzanne Hammersley, Maggie H Shepherd, Robert C Andrews and 2 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open diabetes research & care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02921906 (Assessing the Effect of Food Composition on Postprandial Insulin Secretion in KCNJ11 Neonatal Diabetes), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02921906 nacompletednot on this map

Assessing the Effect of Food Composition on Postprandial Insulin Secretion in KCNJ11 Neonatal Diabetes (FoND Study)

TypeinterventionalSponsorRoyal Devon and Exeter NHS Foundation TrustRan2016 to 2022Enrolled16ConditionsNeonatal DiabetesArmsHigh protein meal, High carbohydrate meal, Paracetamol, Fasting state - sulphonylurea only
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Genes · 2022
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Pamela BowmanInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.ORCID 0000-0002-5241-7700
Timothy J McDonaldInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Bridget A KnightInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Sarah E FlanaganInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Maria LeveridgeRoyal Devon and Exeter NHS Foundation Trust, Exeter, Devon, UK.
Steve R SpaullExeter NIHR Clinical Research Facility, Exeter, Devon, UK.
Beverley M ShieldsInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.ORCID 0000-0003-3785-327X
Suzanne HammersleyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Maggie H ShepherdInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Robert C AndrewsInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
Kashyap A PatelInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.ORCID 0000-0002-9240-8104
Andrew T HattersleyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, Devon, UK.
University of Exeter · GBNIHR Exeter Clinical Research Facility · GBRoyal Devon & Exeter NHS Foundation Trust · GB

Funding

Department of Health ICA-SCL-2016-02-003Department of Health NIHR-HCS-P12-03-03Diabetes UK 16/0005407Wellcome Trust 098395/Z/12/ZWellcome Trust 105636/Z/14/ZWellcome Trust 110082/Z/15/Z
6 · The paper itself

Abstract

Objective: Insulin secretion in sulfonylurea-treated Research design and methods: 5 adults with sulfonylurea-treated Results: In controls, glucose values after carbohydrate and protein/fat were similar (median glucose tAUC Conclusions: Individuals with sulfonylurea-treated Trial registration number: NCT02921906.

Indexed as

AdultCase-Control StudiesDiabetes MellitusFemaleGastric EmptyingHumansInsulin SecretionKcnj11 ChannelMaleMealsMetabolic Networks and PathwaysMutation, MissensePostprandial PeriodPotassium Channels, Inwardly RectifyingSulfonylurea CompoundsYoung AdultKcnj11 ChannelPotassium Channels, Inwardly RectifyingSulfonylurea Compoundsinsulin secretionpermanent Neonatal DiabetesphysiologySU (Sulfonylurea)

Identifiers

PMID31908791
PMCPMC6936449
OpenAlexW2995540225

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.