Evidence map›Paper›PMID 31908643›Full record

ArticleJournal of Taibah University Medical Sciences2019

Correlations between serum inflammatory markers and comorbidities in patients with end-stage renal disease.

Asmahan K Eloueyk, Rashad Y Alameddine, Bilal A Osta, Dania M Awad

Open access · goldAbstract read
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  6. Blood Glucose and Renal Function Evaluation in Patients with Viral Hepatitis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Asmahan K EloueykDepartment of Biological Sciences, Beirut Arab University, Faculty of Science, Debbieh, Lebanon.
Rashad Y AlameddineOrange Nassau Governmental Hospital, Tripoli, Lebanon.
Bilal A OstaDepartment of Biological Sciences, Beirut Arab University, Faculty of Science, Debbieh, Lebanon.
Dania M AwadLaboratiore de biotechnologie, Doctoral School of Sciences and Technology, Faculty of Public Health, Lebanese University, Tripoli, Lebanon.
Beirut Arab University · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChronic inflammatory processes are common in patients with renal disease, especially those with end-stage renal disease (ESRD), in whom inflammatory markers have been shown to increase with renal function deterioration. ESRD is usually accompanied by other chronic diseases such as hypertension and diabetes. The relationships between ESRD comorbidities and serum levels of inflammatory markers have not yet been fully understood. The aim of this study was to assess serum levels of inflammatory markers in different ESRD cohorts and to investigate the correlations between these inflammatory markers and disease comorbidities.

methodsA total of 147 patients were grouped according to their comorbid conditions: diabetic only, hypertensive only, diabetic and hypertensive, and neither diabetic nor hypertensive. Serum levels of C-reactive protein (CRP), tumour necrosis factor-alpha (TNF-α), and interleukin-1-beta (IL-1β) were investigated in different ESRD cohorts by enzyme-linked immunosorbent assay.

resultsSerum CRP and TNF-α levels were high in diabetic patients (

conclusionsOur results showed that, in ESRD patients, CRP and TNF-α seem to be largely affected by patients' comorbidities, unlike IL-1β, which might be affected more by the dialysis process even in the absence of comorbidities.

Indexed as

CytokinesDiabetesEnd stage kidney diseaseHypertension

Identifiers

PMID31908643
PMCPMC6940637
OpenAlexW2983627919

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.