ArticleThe Malaysian journal of medical sciences : MJMS2019
A Cross-Sectional Study of Neutrophil-to-Lymphocyte Ratio in Diagnosing Acute Appendicitis in Hospital Melaka.
Article in The Malaysian journal of medical sciences : MJMS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 25 citations in OpenAlex.
- Diagnostic Accuracy of Inflammatory Biomarkers in Differentiating Acute Appendicitis From Other Acute Abdomen and Predicting Disease Severity: A Prospective Comparative Cross-Sectional Study.Health science reports · 2026Article
- Diagnostic value of CAR, HALP, and SII for predicting complicated appendicitis: a reassessment of inflammatory indices.BMC surgery · 2026Observational
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- A novel combined neutrophil-platelet score for diagnosing complicated appendicitis: a retrospective and prospective cohort study.Acta cirurgica brasileira · 2026Article
- Systemic inflammatory indices and age-dependent severity in acute appendicitis: a retrospective cohort study.Frontiers in immunology · 2025Article
- Barriers to accessing appendectomy in the public sector health system in the Western Cape Province, South Africa.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2024Article
- Diagnostic value of laboratory parameters for complicated appendicitis: A two‑center study.Biomedical reports · 2024Article
- RAMA-WeRA Risk Score in Predicting the Ruptured Appendicitis in Emergency Department; a Multicenter Study for External Validation.Archives of academic emergency medicine · 2024Article
- Factors Contributing to Delays to Accessing Appendectomy in Low- and Middle-Income Countries: A Scoping Review.World journal of surgery · 2023Article
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- COVID-19 pandemic changed the management and outcomes of acute appendicitis in northern Beijing: A single-center study.World journal of clinical cases · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute appendicitis is one of the most common surgical emergencies. However, its proper diagnosis is complicated. This study aims to evaluate the ability of the neutrophil-to-lymphocyte ratio (NLR) to diagnose acute appendicitis in pre-operative state.
methodsHistopathological examination of appendicectomies conducted between 2016 and 2017 in Melaka Hospital, Malaysia were traced and categorised into three groups: i) G1 (normal appendix), ii) G2 (acute appendicitis) and iii) G3 (perforated appendicitis). The reports were randomised and a total of 338 samples were collected. NLR values were compared between the three different groups and analysed.
resultsThe median values of NLR for G1, G2 and G3 were 2.37, 5.25 and 9.27, respectively. We found a statistically significant difference in NLR between G1 and G2 (
conclusionNLR, with a sensitivity of 75.23% and specificity of 68.70%, is a useful and reliable adjunct in diagnosing acute appendicitis. Hence, it will help in reducing the rate of negative appendicectomies.
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