ArticleRisk management and healthcare policy2019
The Association Between Subclinical Hypothyroidism and Sleep Quality: A Population-Based Study.
Article in Risk management and healthcare policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- The effect of photobiomodulation therapy on fatigue and behavioural status in patients with Hashimoto's thyroiditis.Lasers in medical science · 2026Trial
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- Evaluation of sleep quality and obstructive sleep apnea in non-alcoholic fatty liver disease: a cross-sectional study.BMC gastroenterology · 2026Article
- Subjective-Device-Estimated Sleep Discrepancies in Late-Life Depression: Agreement and Associated Factors.Alpha psychiatry · 2026Article
- The correlations of insomnia symptoms with psychopathology and hematological parameters as well as gender differences in patients with schizophrenia.Scientific reports · 2026Article
- Sleep aspects and subclinical hypothyroidism: a four-year follow-up of the ELSA-Brasil study.Archives of endocrinology and metabolism · 2026Article
- Sleep patterns, depression, and incident thyroid diseases: a large cohort study of 371,627 United Kingdom biobank participants.BMC public health · 2026Article
- Polysomnographic evaluation of sleep quality and quantitative variables in patients of hypothyroidism.Journal of family medicine and primary care · 2025Article
- Sleep quality and its determinants in patients with thyroid eye disease: a cross-sectional study.European journal of medical research · 2025Article
- Sleep factors and risk of thyroid cancer, nodules and dysfunction: Mendelian randomization study.Gland surgery · 2025Article
- Association between phthalate exposure and sleep quality in pregnant women: Results from the Korean Children's Environmental Health Study with repeated assessment of exposure.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Evaluating the Spectrum of Sleep Abnormalities in Patients With Primary Hypothyroidism.Cureus · 2024Article
- Causal relationship between insomnia and thyroid disease: A bidirectional Mendelian randomization study.Brain and behavior · 2024Article
- Sensitivity to thyroid hormones is associated with sleep duration in the euthyroid population with depression degree lower than moderate.Scientific reports · 2024Article
- The Relationship Between Thyroid Dysfunction and Sleep Quality Among Population of Saudi Arabia.International journal of general medicine · 2024Article
- Sex and Sleep Disruption as Contributing Factors in Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Review
- Association between small intestine bacterial overgrowth and psychiatric disorders.Frontiers in endocrinology · 2024Review
- The relationship between autoimmune thyroid disease, thyroid nodules and sleep traits: a Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Emotional and behavioral features associated with subclinical hypothyroidism in children and adolescents with Down syndrome.Frontiers in psychology · 2023Article
- Circadian rhythm in restless legs syndrome.Frontiers in neurology · 2023Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThe relationship between subclinical hypothyroidism (SHYPO) and sleep quality is still unclear. Our objective was to compare the sleep quality between SHYPO patients and a control group with normal thyroid function.
methodsA total of 2224 patients with SHYPO and 12,622 euthyroid (EUTH) control group patients were included in the present study. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. The sleep outcomes were compared to explore the association between SHYPO and sleep quality. Furthermore, we tried to identify the risk factors of poor sleep in SHYPO patients.
resultsCompared to the EUTH control patients, SHYPO patients had a higher PSQI score (6.83 ± 2.67 vs 6.64 ± 2.63, p =0.004) and a higher proportion of poor sleepers (67.09% vs 64.75%, p =0.033). Moreover, subjects with SHYPO were associated with poorer sleep (Odd Ratio (OR) 1.120, 95% Confidence Intervals (CI) 1.016 to 1.235, p =0.023), longer sleep latency (OR 1.162, 95% CI 1.053 to 1.282, p =0.003), and shorter sleep duration (OR 1.148, 95% CI 1.019 to 1.293, p =0.023) after adjusting for potential confounders. Furthermore, we found that lower age, lower body mass index, and women were risk factors for poor sleep quality in SHYPO patients.
conclusionOur findings suggest a relationship between SHYPO and poor sleep quality in a large Chinese population.
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