ArticleClinical interventions in aging2019
Identification of Frailty and Its Risk Factors in Elderly Hospitalized Patients from Different Wards: A Cross-Sectional Study in China.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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49 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Systematic review and meta-analysis of the prevalence of frailty and pre-frailty amongst older hospital inpatients in low- and middle-income countries.Age and ageing · 2025Pooled it
- Exploring the Median Effective Dose of Ciprofol for Anesthesia Induction in Elderly Patients: Impact of Frailty on EDDrug design, development and therapy · 2024Trial
- Comparing Two Frailty Tools for the Prediction of Mortality in Older People Admitted to Hospital in Tanzania: A Prospective Cohort Study.Health science reports · 2026Article
- Frailty Among the Older Adults in Bangladesh: A Comparative Analysis of Rural and Urban Populations.Health science reports · 2026Article
- Comparison of diagnostic characteristics of four frailty screening tools in maintenance hemodialysis patients.International urology and nephrology · 2026Article
- Is pre-stroke frailty as determined by the Clinical Frailty Scale version 2.0 associated with stroke outcomes?Singapore medical journal · 2026Article
- Intelligent health promotion system-based construction and implementation of exercise intervention for older adults with frailty and prefrailty.Frontiers in aging · 2026Article
- Knowledge, attitude, and practice of nurses towards frailty syndrome: a multicenter cross-sectional survey in Fujian Province, China.Frontiers in medicine · 2026Article
- Comparison of the long-term prognostic value of different frailty instruments in older inpatients: a 5-year prospective cohort study.European journal of medical research · 2025Article
- Frailty in older adults patients: a prospective observational cohort study on subtype identification.European journal of medical research · 2025Observational
- Osteosarcopenia, osteoarthritis and frailty: a two-sample Mendelian randomization study.Aging clinical and experimental research · 2025Article
- Associated factors of frailty among community-dwelling older adults with multimorbidity from a health ecological perspective: a cross-sectional study.BMC geriatrics · 2025Article
- Frailty and nutritional assessments for predicting postoperative complications in older adults undergoing non-cardiac surgery.Frontiers in medicine · 2025Article
- Impact of Combined Cognitive and Physical Impairments on Long-Term Prognosis in Elderly Cardiovascular Disease Patients: A Prospective Cohort Study.Clinical interventions in aging · 2025Article
- Comparison and identification of serum metabolomic profiles in Stage B and Stage C ejection fraction preserved heart failure.Frontiers in cardiovascular medicine · 2025Article
- Development and Validation of Nomogram to Predict Frailty for Older Patients Undergoing Abdominal Surgery.Clinical interventions in aging · 2025Article
- The current situation and associated factors of preoperative frailty in elderly patients undergoing abdominal surgery.Perioperative medicine (London, England) · 2024Article
- Low transthyretin concentration linked to adverse prognosis in elderly inpatients.BMC geriatrics · 2024Article
- The weight-adjusted waist index and frailty: A cohort study from the China Health and Retirement Longitudinal Study.The journal of nutrition, health & aging · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo survey the difference of frailty prevalence in elderly inpatients amongdifferent wards; to compare the diagnostic performance of five frailty measurements (Clinical Frailty Scale [CFS], FRAIL, Fried, Edmonton, Frailty Index [FI]) in identifying frailty; and to explore the risk factors of frailty in elderly inpatients. PARTICIPANTS AND
methodsThis was a cross-sectional study including 1000 inpatients (mean age 75.2±6.7 years, 51.5% male; 542, 229, and 229 patients from cardiology, non-surgical, and surgical wards, respectively) in a tertiary hospital from September 2018 to February 2019. We applied the combined index to integrate the five frailty measurements mentioned above as the gold standard of frailty diagnosis. Multivariate logistic regression models were used to determine the independent risk factors of frailty.
resultsFrailty prevalence was 32.3% (Fried), 36.2% (CFS), 19.2% (FRAIL), 25.2% (Edmonton), 35.1% (FI) in all patients. The frailty was more common in non-surgical wards, regardless of the frailty assessment tools used (non-surgical wards: 27.5% to 51.5%; cardiology ward: 14.9% to 29.3%; surgical wards: 18.8% to 41.9%). CFS≥5 showed a sensitivity of 94.1% and a specificity of 85.2% for all patients. FI≥0.25 showed a sensitivity of 94.8% and a specificity of 87.0% for all patients. Age [odds ratio (OR) = 1.089, P<0.001], education level (OR = 0.782, P=0.001), heart rate (OR = 1.025, P<0.001), albumin (OR = 0.911, P=0.002), log D-dimer (OR = 2.940, P<0.001), ≥5 comorbidities (OR = 2.164, P=0.002), and ≥5 medications (OR = 2.819, P<0.001) were independently associated with frailty in all participants.
conclusionFrailty is common among elderly inpatients, especially in non-surgical wards. CFS is a preferred screening tool and FI may be an optimal assessment tool. Old age, low educational level, fast heart rate, low albumin, high D-dimer, ≥5 comorbidities, and polypharmacy are independent risk factors of frailty in elderly hospitalized patients.
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