ArticleClinical interventions in aging2019
Risk Factors For Hyperuricemia In Chinese Centenarians And Near-Centenarians.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Dioscin regulates oxidative stress and autophagy in uric acid-induced HK-2 cells through the P62-KEAP1-NRF2 signaling pathway.BMC nephrology · 2025Article
- Impact of health literacy, social support, and socioeconomic position on the serum uric acid level in asymptomatic hyperuricaemia patients in China: a structural equation model.BMC public health · 2024Article
- An artificial neural network model for evaluating the risk of hyperuricaemia in type 2 diabetes mellitus.Scientific reports · 2024Article
- Comment on "Hyperuricemia may be associated with muscle wellness in older adults".International urology and nephrology · 2024Article
- Development and validation of a prediction model for hyperuricemia risk in hypertensive patients.American journal of cardiovascular disease · 2024Article
- Study on risk factor analysis and model prediction of hyperuricemia in different populations.Frontiers in nutrition · 2024Article
- Association between alcohol consumption and risk of hyperuricaemia among adults: a large cross-sectional study in Chongqing, China.BMJ open · 2023Article
- Excessively Increased Skeletal Muscle Mass of the Bilateral Lower Limbs is Associated with Hyperuricemia in Females with Polycystic Ovarian Syndrome.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Prevalence and Risk Factors of Hyperuricemia in the Urban Health Checkup Population in Xinjiang, China: A Cross-Sectional Study.Risk management and healthcare policy · 2023Article
- Prevalence and associated factors of hyperuricemia among Chinese patients with diabetes: a cross-sectional study.Therapeutic advances in endocrinology and metabolism · 2023Article
- The serum uric acid is longitudinally related to patients global assessment of disease activity in male patients with axial spondyloarthritis.BMC musculoskeletal disorders · 2022Article
- Risk Factors and Cardiovascular Disease in the Elderly.Reviews in cardiovascular medicine · 2022Review
- Association of self-reported snoring and hyperuricaemia: a large cross-sectional study in Chongqing, China.BMJ open · 2022Article
- Association of eating out frequency and other factors with serum uric acid levels and hyperuricemia in Chinese population.European journal of nutrition · 2022Article
- The Association Between Spicy Food Intake and Risk of Hyperuricemia Among Chinese Adults.Frontiers in public health · 2022Article
- Prevalence of hyperuricemia and the population attributable fraction of modifiable risk factors: Evidence from a general population cohort in China.Frontiers in public health · 2022Article
- Dietary Inflammatory Index and the Risk of Hyperuricemia: A Cross-Sectional Study in Chinese Adult Residents.Nutrients · 2021Article
- Association between serum uric acid and major chronic diseases among centenarians in China: based on the CHCCS study.BMC geriatrics · 2021Article
- Dietary vitamin intake and risk of metabolic syndrome among centenarians in China.Experimental and therapeutic medicine · 2021Article
- Neck Circumference Is Associated With Hyperuricemia in Women With Polycystic Ovary Syndrome.Frontiers in endocrinology · 2021Article
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHyperuricemia is an important potential pathogenic factor for hypertension, cardiovascular disease and stroke. The current study aimed to investigate the prevalence of hyperuricemia and its relationship to lifestyle characteristics and dietary habits in centenarians and near-centenarians. PATIENTS AND
methodsIn total, 966 centenarians and 788 near-centenarians were included. Community-based surveys were conducted to collect information about lifestyle. Blood examinations were performed using enzymatic assays. T-tests and χ2 tests were used to investigate significant indicators of hyperuricemia, and multivariate logistic regression was used to analyze the related risk factors. A comprehensive analysis of nineteen modifiable factors, including lifestyle characteristics, dietary habits, general characteristics and blood test indexes, was conducted.
resultsThe prevalence of hyperuricemia was 29.02%. The percentage of men, waist circumference (WC), waist-hip ratio, estimated glomerular filtration rate (eGFR), levels of total protein (TP), alanine aminotransferase, aspartate aminotransferase, triglycerides, high-density lipoprotein cholesterol, serum homocysteine, serum uric acid, serum urea and serum creatinine, passive smoking, alcohol consumption, snoring, preference for fried flavors, and meat, seafood and vegetable consumption were significantly different between the hyperuricemia group and the normouricemia group (p<0.05). Multivariate logistic regression analysis showed that WC (OR=1.020), eGFR (OR=0.960), TP level (OR=1.038), serum urea level (OR=1.154), passive smoking (OR=2.589), snoring (OR=2.003), meat consumption (OR=2.506), seafood consumption (OR=1.422) and vegetable consumption (OR=0.521) were significantly associated with the risk of hyperuricemia (p<0.05).
conclusionLow eGFR and vegetable consumption, high WC, TP, and serum urea levels, passive smoking, snoring, and high meat and seafood consumption were independent risk factors for hyperuricemia. It is recommended that people at high risk for hyperuricemia should actively limit their intake of fried food, alcohol and purine-rich food, increase their intake of fresh vegetables, actively treat sleep apnea syndrome, avoid passive smoking, maintain a healthy WC and seek to improve their kidney and liver function.
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