ArticleClinical interventions in aging2019
Frailty in Older Patients with Acute Coronary Syndrome in Vietnam.
Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Association of frailty and pre-frailty with cardiovascular mortality: a meta-analysis of 26 cohort studies.Frontiers in public health · 2025Pooled it
- Prevalence and adverse outcomes of frailty in older patients with acute myocardial infarction after percutaneous coronary interventions: A systematic review and meta-analysis.Clinical cardiology · 2023Pooled it
- Frailty and sex differences in blood pressure control in older adults.Scientific reports · 2026Article
- Frailty in older patients with cancer in Vietnam.BMC geriatrics · 2026Observational
- Frailty scale with the best prediction of mortality in individuals diagnosed with acute coronary syndrome: systematic review and meta-analysis.Journal of geriatric cardiology : JGC · 2026Article
- The role of frailty in older adults with Non-ST-elevation acute coronary syndrome: a Chinese population-based cohort study.Aging clinical and experimental research · 2025Article
- Frailty and prescriptions of secondary prevention medications in older people with diabetes and coronary heart disease-An observational study in Vietnam.Australasian journal on ageing · 2025Observational
- Development and validation of machine learning-derived frailty index in predicting outcomes of patients undergoing percutaneous coronary intervention.International journal of cardiology. Heart & vasculature · 2024Article
- Adaptation of the comprehensive rheumatologic assessment of frailty (CRAF) as a multidimensional frailty screening tool in patients with rheumatoid arthritis in Vietnam.BMC rheumatology · 2024Article
- Stroke and frailty index: a two-sample Mendelian randomisation study.Aging clinical and experimental research · 2024Article
- Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis.World journal of clinical cases · 2024Article
- Fried Frailty Phenotype in Elderly Patients with Chronic Coronary Syndrome: Prevalence, Associated Factors, and Impact on Hospitalization.Journal of multidisciplinary healthcare · 2024Article
- The impact of frailty on in-hospital complications in elderly patients with acute coronary syndrome.Journal of geriatric cardiology : JGC · 2023Article
- The Frail Scale - A Risk Stratification in Older Patients with Acute Coronary Syndrome.Journal of multidisciplinary healthcare · 2023Article
- Association between Perceived Health-Related Quality of Life and Depression with Frailty in the FRASNET Study.International journal of environmental research and public health · 2022Observational
- Clinical Study of Mesenchymal Stem/Stromal Cell Therapy for the Treatment of Frailty: A Proposed Experimental Design for Therapeutic and Mechanistic Investigation.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Frailty Scores and Their Utility in Older Patients with Cardiovascular Disease.Interventional cardiology (London, England) · 2021Review
- A Pilot Study of the Clinical Frailty Scale to Predict Frailty Transition and Readmission in Older Patients in Vietnam.International journal of environmental research and public health · 2020Article
- Article
- Differences in Healthcare Services Utilization Between Urban and Rural Older Persons in Vietnam: Evidence from a National Survey.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere has been limited evidence about frailty in older patients with acute coronary syndrome (ACS) in Vietnam.
aim(1) To investigate the prevalence of frailty in older patients hospitalised with ACS and its associated factors; (2) To investigate the impact of frailty on percutaneous coronary intervention (PCI) and adverse outcomes in this population.
methodsPatients aged ≥60 with ACS admitted to two teaching hospitals in Vietnam were recruited from 9/2017 to 4/2018. Frailty was defined by the Reported Edmonton Frail Scale. Multivariate logistic regression was applied to investigate the associated factors of frailty and the impact of frailty on PCI and adverse outcomes.
resultsThere were 324 participants, mean age 73.5±8.3, 39.2% female. The prevalence of frailty was 48.1%. Advanced age, female gender, history of hypertension, heart failure, stroke and chronic kidney disease were significantly associated with a frailty status. Overall, 50.3% of the participants received PCI (58.3% in the non-frail vs 41.7% in the frail, p=0.003). However, frailty did not have an independent impact on PCI (adjusted OR 0.66, 95% CI 0.41-1.08). Frailty was significantly associated with increased risk of having arrhythmia during hospitalisation (adjusted OR 2.24, 95% CI 1.32-3.80), hospital-acquired pneumonia (adjusted OR 2.27, 95% CI 1.24-4.17), in-hospital mortality (adjusted OR 3.02, 95% CI 1.35-6.75), 30-day mortality (adjusted OR 3.28, 95% CI 1.59-6.76), and 30-day readmission (adjusted OR 2.53, 95% CI 1.38-4.63).
conclusionIn this study, frailty was present in nearly half of older patients with ACS and was associated with increased adverse outcomes. These findings suggest that frailty screening should be performed in older patients with ACS in Vietnam.
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