Evidence map›Paper›PMID 31907994›Full record

ArticleJournal of clinical laboratory analysis2020

Assessment of serum sialic acid correlated with C3 in children with Mycoplasma pneumoniae pneumonia.

Yu-Mei Mi, Qi Qi, Li Zhang, Xiao-Fang Wang, Zhi-Min Chen, Chun-Zhen Hua

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of breastfeeding andFrontiers in immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yu-Mei MiDivision of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Qi QiDepartment of Infectious Disease, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, China.
Li ZhangDivision of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Xiao-Fang WangDepartment of Pediatrics, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Zhi-Min ChenDivision of Respiration, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Chun-Zhen HuaDivision of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.
Children's Hospital of Zhejiang University · CNAffiliated Hospital of Hangzhou Normal University · CNHangzhou Red Cross Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDifferent from the diagnosis of bacterial infections, Mycoplasma pneumoniae pneumonia (MPP) is still lacking of convenient non-specific laboratory parameters.

methodA total of 125 children with MPP were included in the MPP group and 89 children with Mycoplasma-negative pneumonia were included in the control group, and the sera were collected from the children at both the acute and recovery stages in the two groups.

resultsThe sialic acid and C3 in the MPP group were significantly higher than those in the control group both at the acute and at the recovery stage. On the other hand, the sialic acid and C3 at the acute stage were significantly higher than those at the recovery stage in the MPP group. However, in the control group, the sialic acid and C3 demonstrated IgG exhibited no significant change between the acute stage and the recovery stage. Lastly, positive correlations between sialic acid level and C3 level were identified in the MPP group at both acute and recovery stages.

conclusionOur study demonstrated that the serum sialic acid correlated with C3 specifically increased in children with MPP, indicating that it might be the important non-specific parameters in the diagnosis of MPP.

Indexed as

AdolescentCase-Control StudiesChildChild, PreschoolComplement C3Complement C4C-Reactive ProteinFemaleHumansImmunoglobulin GInfantMaleMycoplasma pneumoniaeN-Acetylneuraminic AcidPneumonia, MycoplasmaComplement C3Complement C4C-Reactive ProteinImmunoglobulin GN-Acetylneuraminic AcidC3childrenMycoplasma pneumoniaepneumoniasialic acid

Identifiers

PMID31907994
PMCPMC7083476
OpenAlexW2999410461

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.