ArticleMolecular imaging and biology2020
Glutamate-Weighted CEST Contrast After Removal of Magnetization Transfer Effect in Human Brain and Rat Brain with Tumor.
Article in Molecular imaging and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Multi-Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration.Magnetic resonance in medicine · 2026Article
- High-resolution glutamate-weighted mapping of in vivo mouse brain across age with chemical exchange saturation transfer MRI.GeroScience · 2026Article
- CEST MRI reveals nicotine-induced alterations in glutamate-associated molecular connectivity in the mouse brain.Frontiers in neuroscience · 2026Article
- CEST MRI assessment of HIV-1-associated neurometabolic impairments in a humanized mouse model.NeuroImmune pharmacology and therapeutics · 2025Article
- Double-Step R1rho-Based Lorentzian Fitting (DROF): A New CEST Analysis Approach and Its Comparison With Existing Methods.NMR in biomedicine · 2025Article
- Mapping hippocampal glutamate in healthy aging withFrontiers in aging neuroscience · 2024Article
- Molecular Imaging of Brain Tumors and Drug Delivery Using CEST MRI: Promises and Challenges.Pharmaceutics · 2022Review
- Relaxation-Compensated Chemical Exchange Saturation Transfer MRI in the Brain at 7T: Application in Relapsing-Remitting Multiple Sclerosis.Frontiers in neurology · 2022Article
- Comparisons of Glutamate in the Brains of Alzheimer's Disease Mice Under Chemical Exchange Saturation Transfer Imaging Based on Machine Learning Analysis.Frontiers in neuroscience · 2022Article
- Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo.Current opinion in chemical biology · 2021Review
- Temporal Changes in In Vivo Glutamate Signal during Demyelination and Remyelination in the Corpus Callosum: A Glutamate-Weighted Chemical Exchange Saturation Transfer Imaging Study.International journal of molecular sciences · 2020Article
- Regional Mapping of Brain Glutamate Distributions Using Glutamate-Weighted Chemical Exchange Saturation Transfer Imaging.Diagnostics (Basel, Switzerland) · 2020Article
- Evaluation of the efficacy of creatine chemical exchange saturation transfer imaging in assessing testicular maturity.Reproductive medicine and biologyArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeTo mitigate the effect of magnetization transfer (MT) from glutamate-weighted chemical exchange saturation transfer (GluCEST) contrast in healthy human brain and its demonstration in a rat brain tumor model. PROCEDURES: GluCEST data was acquired from six healthy human volunteers at 7T and on a rat brain with tumor at 9.4 T. Single voxel proton magnetic resonance spectroscopy (
resultsBetter accuracy of fitting off-resonance Z-spectra was achieved with super-Lorentzian (σ = 0.0009) and Lorentzian (σ = 0.0017) compared to other lineshapes. There was significant (p < 0.01) increase in GluCEST
conclusionsRemoval of MT effect from Z-spectra using Lorentzian lineshape increased the specificity of GluCEST contrast to glutamate in healthy human brain and was demonstrated in rat brain tumor model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.