Evidence map›Paper›PMID 31907763›Full record

ArticleJournal of gastrointestinal cancer2021

Colon Cancer and Diverticular Disease Association: a Case-Control Study.

Maggie B Kearney, Jeffrey M Williams, Mark H Ebell

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maggie B KearneyUniversity of Georgia College of Public Health, 100 Foster Rd., Athens, GA, 30606, USA. maggiebkearney@gmail.com.ORCID https://orcid.org/0000-0001-5469-339X
Jeffrey M WilliamsAthens Gastroenterology Association, 3320 Old Jefferson Rd., Athens, GA, 30607, USA.
Mark H EbellUniversity of Georgia College of Public Health, 100 Foster Rd., Athens, GA, 30606, USA.
Georgia College & State University · USMercer University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine if there is an association between diverticular disease and colon cancer diagnoses with a secondary outcome of assessing other known risk factors for colon cancer. Colon cancer and diverticular disease have many shared symptoms and risk factors; the association between the two has been debated for many years.

methods36 cases of colon cancer and 144 age- and sex-matched controls were identified from records at an outpatient endoscopy center in Georgia. These cases and controls then were subject to a retrospective chart review to obtain any known risk factor data points for both diverticular disease and colon cancer. A traditional conditional logistic regression and a stepwise conditional logistic regression model were used to analyze the data using significant data points (P < 0.05).

resultsThe final stepwise model found that systolic blood pressure (aOR = 1.027, 95% CI = 1.001 to 1.053), history of polyps (aOR = 0.106, 95% CI = 0.029 to 0.387), exercise (aOR = 0.311, 95% CI = 0.029 to 0.387), and history of diverticular disease (aOR = 0.269, 95% CI = 0.091 to 0.795) were protective factors significantly associated with colon cancer.

conclusionsPresence and history of the removal of colorectal polyps, presence or history of diverticular disease, and exercise pose as protective factors against development of colon cancer.

Indexed as

ExerciseAgedCase-Control StudiesColonColonic NeoplasmsColonic PolypsColonoscopyDiverticulum, ColonFemaleHumansIncidenceIntestinal MucosaMaleMiddle AgedProtective FactorsRetrospective StudiesColon CancerColorectal PolypsDiverticular DiseaseProtective FactorsScreening

Identifiers

PMID31907763
OpenAlexW3000014104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.