ArticleThe international journal of cardiovascular imaging2020
Increased systolic vorticity in the left ventricular outflow tract is associated with abnormal aortic flow formations in Tetralogy of Fallot.
Article in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Four-dimensional flow cardiovascular magnetic resonance in tetralogy of Fallot: a systematic review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Pooled it
- Mechano-electrical-fluid interaction left-ventricle model for numerical evaluation of aortic valve hemodynamics.Frontiers in bioengineering and biotechnology · 2025Article
- Advanced Imaging Technologies for Assessing Tetralogy of Fallot: Insights Into Flow Dynamics.CJC pediatric and congenital heart disease · 2023Review
- Additional value and new insights by four-dimensional flow magnetic resonance imaging in congenital heart disease: application in neonates and young children.Pediatric radiology · 2021Review
- Circulation derived from 4D flow MRI correlates with right ventricular dysfunction in patients with tetralogy of Fallot.Scientific reports · 2021Article
- 4D flow MRI applications in congenital heart disease.European radiology · 2021Review
- Aortic Vorticity, Helicity, and Aortopathy in Adult Patients with Tetralogy of Fallot: Pilot Study Using Four-Dimensional Flow Magnetic Resonance Images.Pediatric cardiology · 2021Article
- Right Ventricular Flow Vorticity Relationships With Biventricular Shape in Adult Tetralogy of Fallot.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aortopathy is a recognized comorbidity of Tetralogy of Fallot (TOF). Aortic flow in children with repaired TOF is abnormal despite normal aortic valve anatomy and early surgical repair that results in aortic size normalization. The purpose of this study was to investigate the flow hemodynamics inside the left ventricle (LV) of children with repaired TOF using 4D-Flow MRI derived vorticity. Vorticity is the spatial derivative of flow velocity and is sensitive to anatomic and geometric variations. Vorticity was calculated inside the LV of children with repaired TOF having normal aortic size (n = 14) and normal controls (n = 10) during systolic ejection phase. All subjects underwent comprehensive biventricular analysis including the MRI based feature-tracking based LV strain analysis and mechanical dyssynchrony. Right ventricular (RV) volumetric indices along with LV mechanical indices were correlated with LV vorticity. All TOF patients had supraphysiologic helical flow in the ascending aorta. The generated peak systolic vorticity integrated over the LV volume was elevated in TOF group compared to control (median: 1344 vs. 858 s
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Registered trials
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