Evidence map›Paper›PMID 31907335›Full record

ArticleAging2020

Dysregulation of antimicrobial peptide expression distinguishes Alzheimer's disease from normal aging.

Min Wang, I-Feng Peng, Simin Li, Xianda Hu

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  9. Review
  10. Unraveling the Role of Antimicrobial Peptides in Insects.International journal of molecular sciences · 2023
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Min WangDepartment of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
I-Feng PengSuzhou Joekai Biotech LLC, Kunshan, China.
Simin LiDepartment of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Xianda HuBeijing Tibetan Hospital, China Tibetology Research Centre, Beijing, China.
China Tibetology Research Center · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNLeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is an age-related neurodegenerative disease with unknown mechanism that is characterized by the aggregation of abnormal proteins and dysfunction of immune responses. In this study, an integrative approach employing

Indexed as

Gene Expression RegulationAgingAlzheimer DiseaseAmyloid beta-PeptidesAnimalsAnimals, Genetically ModifiedApoptosisBrainDatabases, GeneticDisease Models, AnimalGene Expression ProfilingHigh-Throughput Nucleotide SequencingHumansImmunity, InnateNeuronsPore Forming Cytotoxic ProteinsAmyloid beta-PeptidesPore Forming Cytotoxic ProteinsagingAlzheimer's diseaseantimicrobial peptideDrosophila melanogasterinnate immune system

Identifiers

PMID31907335
PMCPMC6977672
OpenAlexW2999565373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.