Evidence map›Paper›PMID 31907326›Full record

ArticleSexually transmitted infections2020

Sexually transmitted infections in persons living with HIV infection and estimated HIV transmission risk: trends over time from the DC Cohort.

Alessandra Anna Secco, Hana Akselrod, Jonathan Czeresnia, Matthew Levy, Morgan Byrne, Anne Monroe, Jose Lucar, Michael Horberg, Amanda Derryck Castel, Rupali Doshi and 5 more

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Sexually Transmitted Infections in People with Human Immunodeficiency Virus.Infectious disease clinics of North America · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Alessandra Anna SeccoInfectious Diseases, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA allisecco@gmail.com.ORCID 0000-0001-9497-0785
Hana AkselrodInfectious Diseases, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Jonathan CzeresniaInternal Medicine, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Matthew LevyDepartment of Epidemiology and Biostatistics, George Washington University Milken Institute of Public Health, Washington, District of Columbia, USA.
Morgan ByrneDepartment of Epidemiology and Biostatistics, George Washington University Milken Institute of Public Health, Washington, District of Columbia, USA.
Anne MonroeDepartment of Epidemiology and Biostatistics, George Washington University Milken Institute of Public Health, Washington, District of Columbia, USA.ORCID 0000-0003-3201-3845
Jose LucarDivision of Infectious Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Michael HorbergDepartment of Infectious Diseases, Mid-Atlantic Permanente Medical Group, Rockville, Maryland, USA.
Amanda Derryck CastelDepartment of Epidemiology and Biostatistics, George Washington University Milken Institute of Public Health, Washington, District of Columbia, USA.
Rupali DoshiDepartment of Epidemiology and Biostatistics, George Washington University Milken Institute of Public Health, Washington, District of Columbia, USA.
Heather RivasplataInfectious Diseases Section, DC VA Medical Center, Washington, District of Columbia, USA.
Leah SquiresInfectious Diseases Section, DC VA Medical Center, Washington, District of Columbia, USA.
David ParentiInfectious Diseases, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Debra BenatorInfectious Diseases, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
DC Cohort Executive Committee
George Washington University · USMilken Institute · USWashington DC VA Medical Center · USUniversity of Mississippi Medical Center · US

Funding

Terry Beirn CPCRA Clinical Trials UnitUM1AI069503 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI KAN, VIRGINIA · 2012 to 2020
$38.5M
The DC Cohort: A Longitudinal Population-Based Cohort Study of People Living with HIV in Washington, DCR24AI152598 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Amanda Derryck Castel, Marinella Temprosa · 2020 to 2026
$37.9M
CPCRA Clinical Trials UnitU01AI069503 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI GORDIN, FRED M · 2007 to 2011
$33.9M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
DC Partnership for HIV/AIDS Progress (DC PFAP)ZIACL009010 · CLC · CLINICAL CENTER · PI MASUR, HENRY · 2010 to 2025
$0k
NIAID NIH HHS P30 AI117970NIAID NIH HHS R24 AI152598NIAID NIH HHS U01 AI069503NIAID NIH HHS UM1 AI069503
6 · The paper itself

Abstract

objectiveA rise in incidence of STIs has been noted in the USA and in the District of Columbia (DC). We aim to describe changes in incident STIs among persons in care for HIV in Washington, DC as well as trends in HIV viral load among those with incident STIs.

methodsWe conducted a retrospective DC Cohort analysis (n=7810) measuring STI incidence (syphilis, gonorrhoea and chlamydia) as well as incare viral load (ICVL) and percentage with all viral loads less than the limit of detection (%<LLOD) by year (2012-2016) among those with incident STIs.

resultsFrom 2012 to 2016, the incidence of STIs increased: chlamydia from 2.1 to 3.4 cases/100 person-years (p=0.0006), gonorrhoea from 2.1 to 4.0 (p<0.0001), syphilis from 1.7 to 2.6 (p=0.0042) and any STI episode from 5.3 to 8.8 (p<0.0001). STI incidence rates increased for those aged 18-34 (from 13.2 to 23.2 cases/100 person-years, p<0.0001), cisgender men (from 6.5 to 11.5, p<0.0001), non-Hispanic whites (from 8.6 to 16.1, p=0.0003) and men who have sex with men (from 9.3 to 15.7, p<0.0001). During 2012-2016, the ICVL among those with incident STIs improved from 108 to 19 copies/mL and %<LLOD from 23.6% to 55.1%. However, even in 2016, younger participants, cisgender and transgender women, non-Hispanic blacks and Hispanics had higher ICVLs and lower %<LLOD.

conclusionsRates of incident STIs rose among persons in care for HIV in Washington, DC, with improved but not optimal measures of HIV viral suppression. These findings inform focused interventions towards preventing STI transmission and ending the HIV epidemic.

Indexed as

AdolescentAdultAge FactorsBlack or African AmericanChlamydia InfectionsCoinfectionDistrict of ColumbiaEthnicityFemaleGonorrheaHispanic or LatinoHIV InfectionsHumansIncidenceMaleMiddle AgedchlamydiagonorrhoeaHIVincidencesexually transmitted infectionsyphilis

Identifiers

PMID31907326
PMCPMC7031010
OpenAlexW2999970939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.