ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2020
Complementing chronic frailty assessment at hospital admission with an electronic frailty index (FI-Laboratory) comprising routine blood test results.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- The frailty index based on laboratory test data as a tool to investigate the impact of frailty on health outcomes: a systematic review and meta-analysis.Age and ageing · 2023Pooled it
- The Association Between the Clinical Frailty Scale and Adverse Health Outcomes in Older Adults in Acute Clinical Settings - A Systematic Review of the Literature.Clinical interventions in aging · 2023Pooled it
- Methods of Assessing Frailty in the Critically Ill: A Systematic Review of the Current Literature.Gerontology · 2022Pooled it
- Trial
- Patterns of patient worry following major emergency abdominal surgery: a 180-day follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Current management strategies for sarcopenia and frailty in cirrhosis: Missing link in transplant candidacy.World journal of hepatology · 2026Review
- Heart Stress, Frailty and Mortality Risk in two prospective cohorts.medRxiv : the preprint server for health sciences · 2026Article
- Association Between the Frailty Index Based on Laboratory Tests and All-Cause Mortality in Hospitalized Older Adults: Retrospective Cohort Study.JMIR aging · 2025Article
- Can laboratory test-based frailty indices contribute to frailty screening in emergency departments?Age and ageing · 2025Article
- Association Between Preoperative Frailty Using Frailty Index-Laboratory Test and Clinical Outcomes in Older Adults Undergoing Brain Tumor Surgery.Nursing & health sciences · 2025Article
- What can we learn from 68 000 clinical frailty scale scores? Evaluating the utility of frailty assessment in emergency departments.Age and ageing · 2025Article
- Frailty in general medicine patients receiving geriatric medicine liaison services is predictive of adverse outcomes.Australasian journal on ageing · 2025Article
- Role of Frailty Index-Laboratory to predict COVID-19 mortality: a prospective study.Frontiers in public health · 2025Article
- Relationship between the laboratory test-based frailty index and overall mortality in critically ill patients with acute pancreatitis: a retrospective study based on the MIMIC-IV database.Frontiers in medicine · 2025Article
- A machine learning-based model for assessing community-acquired pneumonia severity using routine blood tests.Frontiers in cellular and infection microbiology · 2025Article
- FI-Lab predicts all-cause mortality, but not successful rehabilitation, among patients aged 65 and older after hip or pelvic fracture.Frontiers in medicine · 2025Article
- Impact of hyperkalaemia on renin-angiotensin-aldosterone (RAAS) inhibitor reduction or withdrawal following hospitalisation.Clinical and experimental medicine · 2024Article
- What is the additive value of nutritional deficiency to VA-FI in the risk assessment for heart failure patients?The journal of nutrition, health & aging · 2024Article
- Application of laboratory frailty index in predicting delirium in elderly patients with community-acquired pneumonia.Frontiers in aging · 2024Article
- Comparing frailty prevalence between countries: validation of the Global Burden of Disease study Frailty Index (GBD-FI) in the survey of health, ageing and retirement in Europe.Age and ageing · 2023Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundAcutely ill and frail older adults have complex social and health care needs. It is important to understand how this complexity affects acute outcomes for admission to hospital. We validated a frailty index using routine admission laboratory tests with outcomes after patients were admitted to hospital.
methodsIn a prospective cohort of older adults admitted to a large tertiary hospital in the United Kingdom, we created a frailty index from routine admission laboratory investigations (FI-Laboratory) linked to data comprising hospital outcomes. We evaluated the association between the FI-Laboratory and total days spent in hospital, discharge to a higher level of care, readmission and mortality.
resultsOf 2552 admissions among 1750 older adults, we were able to generate FI-Laboratory values for 2254 admissions (88.3% of the cohort). More than half of admitted patients were women (55.3%) and the mean age was 84.6 (SD 14.0) years. We found that the FI-Laboratory correlated weakly with the Clinical Frailty Scale (CFS;
interpretationWe determined that FI-Laboratory, distinct from baseline frailty, could be used to predict risk of many adverse outcomes. The score is therefore a useful way to quantify the degree of acute illness in frail older adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.