Evidence map›Paper›PMID 31907181›Full record

ArticleAntimicrobial agents and chemotherapy2020

Relationship between Vancomycin MIC and Virulence Gene Expression in Clonal Complexes of Methicillin-Susceptible Staphylococcus aureus Strains Isolated from Left-Sided Endocarditis.

Juan M Pericàs, Carlos Cervera, Cristina Garcia-de-la-Mària, Batu K Sharma-Kuinkel, Rachelle Gonzales, Asunción Moreno, Manel Almela, Carlos Falces, Eduard Quintana, David Fuster and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Juan M Pericàs *Infectious Diseases Clinical Direction-IRB Lleida, Lleida, Spain.
Carlos Cervera *University of Alberta, Edmonton, Canada.
Cristina Garcia-de-la-MàriaHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Batu K Sharma-KuinkelDuke University Medical Center, Durham, North Carolina, USA.
Rachelle GonzalesLA Biomedical Research Institute, Torrance, California, USA.
Asunción MorenoHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Manel AlmelaHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Carlos FalcesHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Eduard QuintanaHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
David FusterHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Francesc MarcoHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Arnold S BayerLA Biomedical Research Institute, Torrance, California, USA.
Vance G FowlerDuke University Medical Center, Durham, North Carolina, USA.
José M MiróHospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain jmmiro@ub.edu.
Hospital Clínic de Barcelona · ESUniversitat de Barcelona · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESDuke Medical Center · USThe Lundquist Institute · USUniversity of Alberta · CA

Funding

Host Susceptibility to S. aureusR01AI068804 · NIAID · DUKE UNIVERSITY · PI FOWLER, VANCE G. · 2007 to 2016
$6.9M
Mentoring Patient Oriented Research in Antibiotic-Resistant BacteriaK24AI093969 · NIAID · DUKE UNIVERSITY · PI FOWLER, VANCE G. · 2011 to 2020
$1.6M
NIAID NIH HHS K24 AI093969NIAID NIH HHS R01 AI068804
6 · The paper itself

Abstract

Higher vancomycin MICs have been associated with more complicated courses and higher mortality rates in patients with

Indexed as

Anti-Bacterial AgentsBiofilmsEndocarditis, BacterialHumansMethicillinMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMultiplex Polymerase Chain ReactionStaphylococcal InfectionsStaphylococcus aureusVancomycinVirulenceVirulence FactorsAnti-Bacterial AgentsMethicillinVancomycinVirulence Factorsagrbiofilmclonal complexemboliendocarditismortalityprognosisStaphylococcus aureusvancomycin MICvirulence factors

Identifiers

PMID31907181
PMCPMC7038266
OpenAlexW2997964702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.