Evidence map›Paper›PMID 31907031›Full record

ArticleBiological research2020

SNHG1 promotes MPP

Jun Zhao, Lijiao Geng, Yong Chen, Chunfang Wu

Open access · goldAbstract read
In one paragraph

Article in Biological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  7. PTEN: a new dawn in Parkinson's disease treatment.Frontiers in cellular neuroscience · 2025
    Review
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  11. AnFrontiers in genetics · 2024
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  12. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jun ZhaoDepartment of Neurology, Huaihe Hospital of Henan University, No. 357 Ximen Street, Kaifeng, 475000, China.
Lijiao GengDepartment of Rehabilitation Medicine, Huaihe Hospital of Henan University, Kaifeng, 475000, China.
Yong ChenDepartment of Neurology, Huaihe Hospital of Henan University, No. 357 Ximen Street, Kaifeng, 475000, China. vwbkwx@163.com.
Chunfang WuDepartment of Neurology, Huaihe Hospital of Henan University, No. 357 Ximen Street, Kaifeng, 475000, China. wuchunfangful@163.com.
Henan University Huaihe Hospital and Huaihe Clinical Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNA small molecule RNA host gene 1 (SNHG1) was previously identified to be relevant with Parkinson's disease (PD) pathogenesis. This work aims to further elucidate the regulatory networks of SNHG1 involved in PD.

methods1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-hydrochloride (MPTP)-induced mice and 1-methyl-4-phenylpyridinium (MPP

resultsIncreased SNHG1 expression was found in midbrain of MPTP-induced PD mice and MPP

conclusionSNHG1 aggravates MPP

Indexed as

1-Methyl-4-phenylpyridiniumAnimalsApoptosisBlotting, WesternCells, CulturedDisease Models, AnimalGene Expression RegulationHumansMaleMiceMice, Inbred C57BLMicroRNAsParkinson DiseaseProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseReal-Time Polymerase Chain Reaction1-Methyl-4-phenylpyridiniumMicroRNAsMTOR protein, humanProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, humanRNA, Long NoncodingTOR Serine-Threonine KinasesIncRNAmiR-153-3pMPP+Parkinson’s diseasePTENSNHG1

Identifiers

PMID31907031
PMCPMC6943908
OpenAlexW2999109080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.