Evidence map›Paper›PMID 31906760›Full record

ArticleInnate immunity2020

Increased oxidative phosphorylation in lymphocytes does not atone for decreased cell numbers after burn injury.

Tony Chao, Belinda I Gomez, Tiffany C Heard, Michael A Dubick, David M Burmeister

Open access · goldAbstract read
In one paragraph

Article in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tony ChaoUnited States Army Institute of Surgical Research, TX, USA.
Belinda I GomezUnited States Army Institute of Surgical Research, TX, USA.
Tiffany C HeardUnited States Army Institute of Surgical Research, TX, USA.
Michael A DubickUnited States Army Institute of Surgical Research, TX, USA.
David M BurmeisterUnited States Army Institute of Surgical Research, TX, USA.ORCID 0000-0002-1256-0158
United States Army Institute of Surgical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acute systemic inflammatory response syndrome (SIRS) and multiorgan dysfunction (MOD) that occur in large burn injuries may be attributed, in part, to immunosuppressive responses such as decreased lymphocytes. However, the mitochondrial bioenergetics of lymphocytes after severe burn injury are poorly understood. The purpose of this study was to examine mitochondrial function of lymphocytes following severe burns in a swine model. Anesthetized Yorkshire swine (

Indexed as

AnimalsBurnsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell CountCell RespirationCells, CulturedCytokinesDisease Models, AnimalHumansLymphocytesMitochondriaOxidative PhosphorylationSwineCytokinesBurnlymphocytemitochondriaoxidative phosphorylationswine

Identifiers

PMID31906760
PMCPMC7903530
OpenAlexW3000467564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.