Evidence map›Paper›PMID 31906588›Full record

ReviewNutrients2020

The Evolving Microbiome from Pregnancy to Early Infancy: A Comprehensive Review.

María Dolores Mesa, Begoña Loureiro, Iris Iglesia, Sergi Fernandez Gonzalez, Elisa Llurba Olivé, Oscar García Algar, María José Solana, Mª Jesús Cabero Perez, Talia Sainz, Leopoldo Martinez and 19 more

Abstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Perturbed maternal microbiota shapes offspring microbiota during early colonization period in mice.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2024
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

María Dolores MesaDepartment of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology "José Mataix", Biomedical Research Center, University of Granada, Parque Tecnológico de la Salud, Avenida del Conocimiento s/n, Armilla, 18100 Granada, Spain.ORCID 0000-0003-4079-6464
Begoña LoureiroNeonatology Unit, University Hospital Cruces, Biocruces Bizkaia Health Research Institute, 48903 Barakaldo, Spain.
Iris IglesiaGrowth, Exercise, Nutrition and Development (GENUD) Research Group, Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-2219-3646
Sergi Fernandez GonzalezBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Elisa Llurba OlivéObstetrics and Gynecology Department, High Risk Unit, Sant Pau University Hospital, 08025 Barcelona, Spain.
Oscar García AlgarBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.ORCID 0000-0001-5708-4362
María José SolanaServicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Departamento de Salud Pública y Materno infantil, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Mª Jesús Cabero PerezHospital Universitario Marqués de Valdecilla, Santander, 39008 Cantabria, Spain.
Talia SainzServicio de Pediatría, Enfermedades Infecciosas y Tropicales, Hospital La Paz, 28046 Madrid, Spain.ORCID 0000-0002-5301-0945
Leopoldo MartinezInstituto de Investigación Hospital la Paz (IdiPAZ), 28029 Madrid, Spain.
Diana Escuder-ViecoDonated Milk Bank, Health Research Institute i + 12, University Hospital 12 de Octubre, Universidad Complutense, 28040 Madrid, Spain.
Anna Parra-LlorcaNeonatal Research Group, Health Research Institute La Fe, University and Polytechnic Hospital La Fe, 46026 Valencia, Spain.
María Sánchez-CampilloDepartment of Physiology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-7177-8341
Gerardo Rodriguez MartinezInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Dolores Gómez RoigBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Myriam Perez GruzBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Vicente Andreu-FernándezBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.ORCID 0000-0001-7183-8706
Jordi ClotetBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Sebastian SailerBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Isabel Iglesias-PlatasBCNatal-Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Sant Joan de Deu and Hospital Clínic), 08028 Barcelona, Spain.
Jesús López-HerceServicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Departamento de Salud Pública y Materno infantil, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6105-9178
Rosa ArasInstituto de Investigación Hospital la Paz (IdiPAZ), 28029 Madrid, Spain.
Carmen Pallás-AlonsoDonated Milk Bank, Health Research Institute i + 12, University Hospital 12 de Octubre, Universidad Complutense, 28040 Madrid, Spain.ORCID 0000-0001-9710-8162
Miguel Saenz de PipaonDepartment of Neonatology La Paz University Hospital, 28046 Madrid, Spain.ORCID 0000-0002-4793-1561
Máximo VentoNeonatal Research Group, Health Research Institute La Fe, University and Polytechnic Hospital La Fe, 46026 Valencia, Spain.ORCID 0000-0003-0061-4742
María GormazNeonatal Research Group, Health Research Institute La Fe, University and Polytechnic Hospital La Fe, 46026 Valencia, Spain.
Elvira Larqué DazaDepartment of Physiology, Faculty of Biology, University of Murcia, 30100 Murcia, Spain.
Cristina CalvoServicio de Pediatría, Enfermedades Infecciosas y Tropicales, Hospital La Paz, 28046 Madrid, Spain.ORCID 0000-0002-6503-3423
Fernando CabañasDepartment of Paediatrics-Neonatology Quironsalud, Madrid University Hospital and Biomedical Research Foundation-IDIPAZ, La Paz University Hospital, 28046 Madrid, Spain.

Funding

The present work has been funded by the PN I+D+I 2008-2011 (Spain), ISCIII- Sub-Directorate General for Research Assessment and Promotion and the European Regional Development Fund (ERDF), RETICS Maternal and Child Health and Development Network, SAMID Ne RD16/0022/0015
6 · The paper itself

Abstract

Pregnancy induces a number of immunological, hormonal, and metabolic changes that are necessary for the mother to adapt her body to this new physiological situation. The microbiome of the mother, the placenta and the fetus influence the fetus growth and undoubtedly plays a major role in the adequate development of the newborn infant. Hence, the microbiome modulates the inflammatory mechanisms related to physiological and pathological processes that are involved in the perinatal progress through different mechanisms. The present review summarizes the actual knowledge related to physiological changes in the microbiota occurring in the mother, the fetus, and the child, both during neonatal period and beyond. In addition, we approach some specific pathological situations during the perinatal periods, as well as the influence of the type of delivery and feeding.

Indexed as

MicrobiotaBacteriaFemaleFetusHumansInfant, NewbornPlacentaPregnancyallergycritical illnessfetusinfancymicrobiomenewbornplacentapregnancysepsis

Identifiers

PMID31906588
PMCPMC7019214

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.