Evidence map›Paper›PMID 31906550›Full record

ArticleInternational journal of environmental research and public health2020

Sex Disparity in Response to Hepatitis B Vaccine Related to the Age of Vaccination.

Andrea Trevisan, Alessandro Giuliani, Maria Luisa Scapellato, Simona Anticoli, Rita Carsetti, Salvatore Zaffina, Rita Brugaletta, Nicoletta Vonesch, Paola Tomao, Anna Ruggieri

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
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  12. Hepatitis B immunisation and immune status of nurses in a regional hospital in central South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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  13. Review
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  18. Sex-Differential and Non-specific Effects of Vaccines Over the Life Course.Current topics in microbiology and immunology · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrea TrevisanDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.
Alessandro GiulianiEnvironment and Health Department, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-4640-804X
Maria Luisa ScapellatoDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy.
Simona AnticoliIstituto Superiore di Sanità, Center for Gender Specific Medicine, 00161 Rome, Italy.ORCID 0000-0003-3238-3280
Rita CarsettiDiagnostic Immunology Unit, Department of Laboratories and B cell Pathophysiology Unit, Immunology Research Area, Bambino Gesù Children Hospital, 00165 Rome, Italy.
Salvatore ZaffinaOccupational Medicine, Health Directorate, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Rita BrugalettaOccupational Medicine, Health Directorate, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Nicoletta VoneschDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian National Workers Compensation Authority, Monte Porzio Catone, 00078 Rome, Italy.
Paola TomaoDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italian National Workers Compensation Authority, Monte Porzio Catone, 00078 Rome, Italy.
Anna RuggieriIstituto Superiore di Sanità, Center for Gender Specific Medicine, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is one of the major infectious hazards for health-care workers (HCWs) because of the frequency of percutaneous exposures to blood or body fluids. For this reason, all HCWs should be vaccinated, including students in medicine and health professional degree programs. The aim of this study was to assess the immune coverage to anti-HBV vaccine and long-lasting protective titres of anti-HBs antibodies in female and male students to evaluate gender-related differences in response to HBV vaccination. Data relative to anti-HBs antibody titre, sex, age, and age at vaccination were collected and analyzed from 5291 Italian students (1812 males and 3479 females) of the graduate courses at the School of Medicine, who underwent the mandatory health surveillance of workers exposed to biological risk. The results indicated that gender affects the immune response to HBV vaccine, particularly evident in the case of females vaccinated after one year of age who exhibited a statistically significant (

Indexed as

VaccinationFemaleHealth PersonnelHepatitis BHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHumansItalyMaleSex FactorsStudentsTime FactorsYoung AdultHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesgenderHBs-antibodieshealth care workershepatitis Bsexvaccine

Identifiers

PMID31906550
PMCPMC6981715

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.