ArticleInternational journal of environmental research and public health2020
Preventability of Colorectal Cancer in Saudi Arabia: Fraction of Cases Attributable to Modifiable Risk Factors in 2015-2040.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Statistical methods for measuring trends in colorectal cancer incidence in registries: A systematic review.Frontiers in oncology · 2022Pooled it
- The association between cigarette smoking and sleep deprivation among adolescents in Gulf Cooperation Council countries: analysis of national surveys.Neurosciences (Riyadh, Saudi Arabia) · 2025Article
- Time trends in colorectal cancer incidence across the BRICS: an age-period-cohort analysis for the GBD 2021.Frontiers in oncology · 2025Article
- Establishing core data elements for colorectal cancer and mapping to FHIR resources: Towards interoperable Iranian health information systems.Journal of education and health promotion · 2025Article
- Review
- Secondhand smoke exposure among adolescents in the gulf cooperation council countries: analysis of global youth tobacco surveys.Scientific reports · 2024Article
- Review
- Demographic and clinical characteristics associated with advanced stage colorectal cancer: a registry-based cohort study in Saudi Arabia.BMC cancer · 2024Article
- Review
- Modifiable risk factors for cancer in the middle East and North Africa: a scoping review.BMC public health · 2024Article
- The burden of colorectal cancer attributable to dietary risk in Middle East and North African from 1990 to 2019.Scientific reports · 2023Article
- Assessing the contribution of nine preventable risk factors attributed to the burden of early onset colorectal cancer in Gulf Cooperation Council (GCC) countries.Preventive medicine reports · 2023Article
- Silver Spike Point Therapy in smoking cessation: What is it and does it work?Saudi medical journal · 2023Review
- Article
- Effect of lycopene as an adjuvant therapy with 5-florouracil in human colon cancer.Saudi journal of biological sciences · 2022Article
- Quality of Life and Needs Assessment of Cancer Patients' Caregivers in the Saudi Culture.Cureus · 2022Article
- Periostin in Angiogenesis and Inflammation in CRC-A Preliminary Observational Study.Medicina (Kaunas, Lithuania) · 2022Observational
- Article
- Tobacco smoking and type 2 diabetes mellitus in Gulf Cooperation Council Countries.Saudi medical journal · 2021Article
- Knowledge, attitude and practice towards early screening of colorectal cancer in Riyadh.Journal of family medicine and primary care · 2020Article
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1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rise in colorectal cancer (CRC) burden is expected around the globe. This study aimed to determine the population attributable fractions (PAFs) of CRC cases contributed by modifiable risk factors in Saudi Arabia. The PAF was calculated for modifiable risk factors with strong evidences of a causal association with CRC. CRC incidence was obtained from the National Cancer Registry, relative risks were retrieved from recent meta-analysis studies, and the prevalence of exposure to risk factors was obtained from national surveys. Conventional statistical formulas were used to calculate PAFs from registered CRC cases, stratified by sex. Three scenarios were proposed to make projections and present the expected effects of prevention interventions on the number of CRC cases in Saudi Arabia for 2025-2040. The results showed the largest fraction of attributable CRC cases among men and women was contributed by physical inactivity (16.13% and 16.45%), followed by excess weight (obesity: 9.71% and 6.93%; overweight: 6.05% and 1.9%); and tobacco smoking (current smoker: 3.04% and 0.18%; former smoker: 3.29% and 0.12%). We estimated that the number of projected cases attributable to physical inactivity, smoking, and excess weight in men and women would increase from 807 and 315 in 2025 to 1360 and 556 in 2040, respectively. In conclusion, physical inactivity, being overweight or obese, and tobacco smoking are major lifestyle factors affecting the incidence of CRC in Saudi Arabia. Prevention interventions and public health programs to reduce their prevalence are warranted.
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