Evidence map›Paper›PMID 31906500›Full record

ReviewCells2020

MicroRNAs: Biological Regulators in Pathogen-Host Interactions.

Stephanie Maia Acuña, Lucile Maria Floeter-Winter, Sandra Marcia Muxel

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
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  4. MicroRNAs and Their Profiling via Single-Cell Sequencing Technologies.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  5. Review
  6. Article
  7. Article
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  9. Review
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  12. Long noncoding RNAs in ubiquitination, protein degradation, and human diseases.Biochimica et biophysica acta. Gene regulatory mechanisms · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Review
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  18. Article
  19. Identification of miRNA Associated withInternational journal of molecular sciences · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephanie Maia AcuñaDepartment of Physiology, Universidade de São Paulo, 05508-090 São Paulo, Brazil.ORCID 0000-0001-6074-4077
Lucile Maria Floeter-WinterDepartment of Physiology, Universidade de São Paulo, 05508-090 São Paulo, Brazil.
Sandra Marcia MuxelDepartment of Physiology, Universidade de São Paulo, 05508-090 São Paulo, Brazil.ORCID 0000-0003-0118-5361
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An inflammatory response is essential for combating invading pathogens. Several effector components, as well as immune cell populations, are involved in mounting an immune response, thereby destroying pathogenic organisms such as bacteria, fungi, viruses, and parasites. In the past decade, microRNAs (miRNAs), a group of noncoding small RNAs, have emerged as functionally significant regulatory molecules with the significant capability of fine-tuning biological processes. The important role of miRNAs in inflammation and immune responses is highlighted by studies in which the regulation of miRNAs in the host was shown to be related to infectious diseases and associated with the eradication or susceptibility of the infection. Here, we review the biological aspects of microRNAs, focusing on their roles as regulators of gene expression during pathogen-host interactions and their implications in the immune response against

Indexed as

BiomarkersCommunicable DiseasesGene Expression RegulationHost-Pathogen InteractionsHumansMicroRNAsMolecular Targeted TherapyBiomarkersMicroRNAsgene expressionhostimmune responsemicroRNAsparasitepathogenpost-transcriptional

Identifiers

PMID31906500
PMCPMC7016591
OpenAlexW2997683321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.