Evidence map›Paper›PMID 31906276›Full record

ArticleNutrients2020

Beneficial Effect of a Multistrain Synbiotic

Pablo Llévenes, Raquel Rodrigues-Díez, Laia Cros-Brunsó, Mᵃ Isabel Prieto, Laura Casaní, Gloria Balfagón, Javier Blanco-Rivero

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
  6. Review
  7. Supplementation with the Symbiotic Formulation ProdefenAntioxidants (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Pablo LlévenesDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, Calle de Arzobispo Morcillo 4, 28029 Madrid, Spain.ORCID 0000-0003-1925-7204
Raquel Rodrigues-DíezDepartment of Pharmacology and Therapeutics, School of Medicine, Universidad Autónoma de Madrid, Calle de Arzobispo Morcillo 4, 28029 Madrid, Spain.ORCID 0000-0002-6348-1505
Laia Cros-BrunsóDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, Calle de Arzobispo Morcillo 4, 28029 Madrid, Spain.
Mᵃ Isabel PrietoResearch Institute University Hospital la Paz (IdIPaz), Calle de Pedro Rico 6, 28029 Madrid, Spain.
Laura CasaníResearch Institute of Santa Creu i Sant Pau Hospital, Carrer de Sant Quintí 77-79, 08041 Barcelona, Spain.ORCID 0000-0002-0139-4588
Gloria BalfagónDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, Calle de Arzobispo Morcillo 4, 28029 Madrid, Spain.
Javier Blanco-RiveroDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, Calle de Arzobispo Morcillo 4, 28029 Madrid, Spain.ORCID 0000-0001-7232-2314
Hospital La Paz Institute for Health Research · ESUniversidad Autónoma de Madrid · ESHospital de Sant Pau · ESHospital Universitario La Paz · ES

Funding

Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares CB16/11/00286Comunidad de Madrid B2017/BMD-3676Italfarmaco, S.A. L.O.U. 83; 0138/2018Juan de la Cierva Program IJCI-2017-31399
6 · The paper itself

Abstract

A high fat diet (HFD) intake is crucial for the development and progression of metabolic syndrome (MtS). Increasing evidence links gut dysbiosis with the metabolic and vascular alterations associated with MtS. Here we studied the use of a combination of various probiotic strains together with a prebiotic (synbiotic) in a commercially available

Indexed as

AnimalsBlood PressureBlood VesselsBody WeightCyclic AMP-Dependent Protein KinasesDietary SupplementsDiet, High-FatDisease Models, AnimalHypertensionInsulin ResistanceMaleMetabolic SyndromeNitric Oxide SynthaseProbioticsRatsRats, WistarCyclic AMP-Dependent Protein KinasesNitric Oxide Synthasehypertensionmetabolic syndromeneuronal nitric oxide synthasenitric oxideperivascular nitrergic innervationprotein kinase asuperior mesenteric arterysynbiotic

Identifiers

PMID31906276
PMCPMC7019517
OpenAlexW2998722030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.