SynthesisNutrients2020
Effectiveness of Interventions for Managing Acute Malnutrition in Children under Five Years of Age in Low-Income and Middle-Income Countries: A Systematic Review and Meta-Analysis.
Synthesis in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Impact of nutrition and health interventions on undernutrition: an overview of systematic reviews.International journal for equity in health · 2025Pooled it
- Effect of Fish-Based Diet on Malnourished Children: A Systematic Review.Iranian journal of medical sciences · 2024Pooled it
- Current evidence on the effectiveness of Ready-to-Use Supplementary Foods in children with moderate acute malnutrition: a systematic review and meta-analysis.Journal of nutritional science · 2023Pooled it
- Ready-to-Use Therapeutic Food (RUTF) Containing Low or No Dairy Compared to Standard RUTF for Children with Severe Acute Malnutrition: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Comparing Azithromycin to Amoxicillin in the Management of Uncomplicated Severe Acute Malnutrition in Burkina Faso: A Pilot Randomized Trial.The American journal of tropical medicine and hygiene · 2022Trial
- Consumer acceptance of a locally produced nutritive food bar in Lao PDR.BMC nutrition · 2026Article
- Formative research on a post-discharge monitoring program using SQ-LNS to reduce acute malnutrition relapse risk in Mali : a qualitative study.BMC public health · 2026Article
- Determinants of Stunting, Wasting, and Underweight Among Children Under 5 Years in India: Evidence From 2019 to 2021 Demographic Health Survey.Health care science · 2026Article
- Prevalence and Determinants of Undernutrition Among Children Under Five in Coastal Bangladesh: A Community-Based Study.Food science & nutrition · 2026Article
- Childhood malnutrition care during the Gaza siege: aprospective program evaluation.BMC nutrition · 2026Article
- Article
- A Global Scoping Review on Alternative Ready-to-Use Therapeutic Foods.Maternal & child nutrition · 2025Article
- Under-nutrition and its associated factors among under-five children across urban and rural settings of Ethiopia: a cross-sectional comparative study.BMC nutrition · 2025Article
- Host-microbiome determinants of ready-to-use supplemental food efficacy in acute childhood malnutrition.JCI insight · 2025Article
- Trends in pulmonary arterial hypertension: insights from Global Burden of Disease 1990-2021.BMJ open · 2025Article
- Analyzing childhood (0-59 months) malnutrition determinants in five West African countries of Gabon, Gambia, Liberia, Mauritania, and Nigeria using a generalized additive mixed model from DHS data.Frontiers in nutrition · 2025Article
- Geospatial disparities in pediatric heart failure care in China: a multicenter cohort study.Frontiers in public health · 2025Article
- Recovery rate and predictors of severe acute malnutrition among under-five children admitted to therapeutic feeding units in Ethiopia: a systematic review and meta-analysis.BMJ nutrition, prevention & health · 2025Article
- Indian perspective on childhood malnutrition: Prevalence, pathophysiology, risk factors, and prevention.World journal of clinical pediatrics · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Childhood malnutrition is a major public health concern, as it is associated with significant short- and long-term morbidity and mortality. The objective of this review was to comprehensively review the evidence for the management of severe acute malnutrition (SAM) and moderate acute malnutrition (MAM) according to the current World Health Organization (WHO) protocol using facility- and community-based approaches, as well as the effectiveness of ready-to-use therapeutic food (RUTF), ready-to-use supplementary food (RUSF), prophylactic antibiotic use, and vitamin A supplementation. We searched relevant electronic databases until 11 February 2019, and performed a meta-analysis. This review summarizes findings from a total of 42 studies (48 papers), including 35,017 children. Limited data show some benefit of integrated community-based screening, identification, and management of SAM and MAM on improving recovery rate. Facility-based screening and management of uncomplicated SAM has no effect on recovery and mortality, while the effect of therapeutic milk F100 for SAM is comparable to RUTF for weight gain and mortality. Local food and whey RUSF are comparable to standard RUSF for recovery rate and weight gain in MAM, while standard RUSF has additional benefits to CSB. Prophylactic antibiotic administration in uncomplicated SAM improves recovery rate and probably improves weight gain and reduces mortality. Limited data suggest that high-dose vitamin A supplementation is comparable with low-dose vitamin A supplementation for weight gain and mortality among children with SAM.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.