ReviewVaccines2019
Safety of Co-Administration Versus Separate Administration of the Same Vaccines in Children: A Systematic Literature Review.
Review in Vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Safety of co-administration of injectable vaccines in individuals under 18 years of age: A systematic literature review.Human vaccines & immunotherapeutics · 2025Pooled it
- The safety of co-administration of Bacille Calmette-Guérin (BCG) and influenza vaccines.PloS one · 2022Trial
- Alternative Childhood Vaccination Schedules in Israel: A Mixed-Methods Study on Prevalence, Patterns, and Public Health Implications.Vaccines · 2026Article
- Age-dependent immune landscapes affect influenza vaccine effectiveness and guide precision strategies.Frontiers in immunology · 2026Review
- Favorable safety and immunogenicity of a combined quadrivalent influenza and recombinant SARS-CoV-2 vaccine in Sprague-Dawley rats for both primary and booster immunization.Frontiers in immunology · 2026Article
- Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals.Human vaccines & immunotherapeutics · 2024Review
- Adverse events following immunization of co- and separate administration of DTaP-IPV/Hib vaccines: A real-world comparative study.Human vaccines & immunotherapeutics · 2024Article
- Adverse event reporting following immunization of hepatitis B vaccine: A 13-year review.Human vaccines & immunotherapeutics · 2024Article
- Non-linear effects of age in reporting of adverse events following influenza immunization in Zhejiang, China.BMC infectious diseases · 2024Article
- Occurrence of adverse events following vaccination in patients with allergies: a prospective study.Central European journal of public health · 2024Article
- Changes in vaccination practices among infants after the introduction of DTaP-IPV/Hib combination vaccines.Vaccine: X · 2024Article
- Analysis of Parents' Attitudes and Knowledge toward Immunization and How These Factors Influence Their Decisions to Vaccinate Their Children against Human Papilloma Virus (HPV).Medicina (Kaunas, Lithuania) · 2023Article
- Understanding vaccine hesitancy with PCV13 in children: Results of a survey in Shanghai, China.PloS one · 2023Article
- Acceptability of the third dose of anti-SARS-CoV-2 vaccine co-administered with influenza vaccine: preliminary data in a sample of Italian HCWs.Human vaccines & immunotherapeutics · 2022Article
- Safety of routine childhood vaccine coadministration versus separate vaccination.BMJ global health · 2022Observational
- Multiple Vaccinations and the Enigma of Vaccine Injury.Vaccines · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The growing number of available vaccines that can be potentially co-administered makes the assessment of the safety of vaccine co-administration increasingly relevant but complex. We aimed to synthesize the available scientific evidence on the safety of vaccine co-administrations in children by performing a systematic literature review of studies assessing the safety of vaccine co-administrations in children between 1999 and 2019, in line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Fifty studies compared co-administered vaccines versus the same vaccines administered separately. The most frequently studied vaccines included quadrivalent meningococcal conjugate (MenACWY) vaccine, diphtheria and tetanus toxoids and acellular pertussis (DTaP) or tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccines, diphtheria and tetanus toxoids and acellular pertussis adsorbed, hepatitis B, inactivated poliovirus and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.