Evidence map›Paper›PMID 31906206›Full record

ReviewJournal of clinical medicine2019

Tachykinins and Kisspeptins in the Regulation of Human Male Fertility.

Víctor Blasco, Francisco M Pinto, Cristina González-Ravina, Esther Santamaría-López, Luz Candenas, Manuel Fernández-Sánchez

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Association of Kisspeptin and KISSReproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  3. The lncRNA Gm8097 is associated with hypospermatogenesis.Clinical and experimental reproductive medicine · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Víctor BlascoIVI-RMA Seville, Avda. República Argentina 58, ES-41011 Seville, Spain.
Francisco M PintoInstituto de Investigaciones Químicas, CSIC, Avenida Americo Vespucio 49, ES-41092 Seville, Spain.
Cristina González-RavinaIVI-RMA Seville, Avda. República Argentina 58, ES-41011 Seville, Spain.
Esther Santamaría-LópezIVI-RMA Seville, Avda. República Argentina 58, ES-41011 Seville, Spain.ORCID 0000-0001-7727-9116
Luz CandenasInstituto de Investigaciones Químicas, CSIC, Avenida Americo Vespucio 49, ES-41092 Seville, Spain.
Manuel Fernández-SánchezIVI-RMA Seville, Avda. República Argentina 58, ES-41011 Seville, Spain.ORCID 0000-0002-1214-2984
IVI Sevilla Clinic · ESInstituto de Investigaciones Químicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility is a global disease affecting one out of six couples of reproductive age in the world, with a male factor involved in half the cases. There is still much to know about the regulation of human male fertility and thus we decided to focus on two peptide families that seem to play a key role in this function: tachykinins and kisspeptins. With this aim, we conducted an exhaustive review in order to describe the role of tachykinins and kisspeptins in human fertility and their possible implications in infertility etiopathogenesis. Many advances have been made to elucidate the roles of these two families in infertility, and multiple animal species have been studied, including humans. All of this knowledge could lead to new advances in male infertility diagnosis and treatment, but further research is needed to clarify all the implications of tachykinins and kisspeptins in fertility.

Indexed as

assisted reproductive technologykisspeptinmale infertilityneurokinintachykinin

Identifiers

PMID31906206
PMCPMC7019842
OpenAlexW2998709682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.