Evidence map›Paper›PMID 31906120›Full record

ArticleVaccines2019

Oral Immunogenicity in Mice and Sows of Enterotoxigenic Escherichia Coli Outer-Membrane Vesicles Incorporated into Zein-Based Nanoparticles.

Jose Matías, Ana Brotons, Santiago Cenoz, Isidoro Pérez, Muthanna Abdulkarim, Mark Gumbleton, Juan M Irache, Carlos Gamazo

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Poly(methyl vinyl ether-Polymers · 2026
    Review
  2. Review
  3. Article
  4. Extracellular vesicles in bone aging: therapeutic strategies and applications.Extracellular vesicles and circulating nucleic acids · 2025
    Review
  5. Review
  6. Analysis of the microbial diversity in takin (Frontiers in microbiology · 2023
    Article
  7. Article
  8. Article
  9. Bacteria-Inspired Nanomedicine.ACS applied bio materials · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jose MatíasDepartment of Microbiology and Parasitology, Institute of Tropical Health, University of Navarra, 31008 Pamplona, Spain.
Ana BrotonsDepartment of Pharmacy and Pharmaceutical Technology, University of Navarra, 31008 Pamplona, Spain.
Santiago CenozBlue Agro Bioscience, Parque Tecnológico Miramón. Paseo Mikeletegi, 54. 20009 San Sebastián, Spain.
Isidoro PérezAgropecuario Obanos, Marcilla, 31340 Navarra, Spain.
Muthanna AbdulkarimSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
Mark GumbletonSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK.
Juan M IracheDepartment of Pharmacy and Pharmaceutical Technology, University of Navarra, 31008 Pamplona, Spain.
Carlos GamazoDepartment of Microbiology and Parasitology, Institute of Tropical Health, University of Navarra, 31008 Pamplona, Spain.
Universidad de Navarra · ESCardiff University · GB

Funding

the Spanish "Ministerio de Economía y Competitividad" RTC-2014-2004-2
6 · The paper itself

Abstract

Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of illness and death in neonatal and recently weaned pigs. The immune protection of the piglets derives from maternal colostrum, since this species does not receive maternal antibodies through the placenta. In the present study, outer membrane vesicles (OMVs) obtained from main ETEC strains involved in piglet infection (F4 and F18 serotypes), encapsulated into zein nanoparticles coated with Gantrez

Indexed as

Escherichia coliETECnanoparticlesouter membrane vesiclesvaccine

Identifiers

PMID31906120
PMCPMC7157560
OpenAlexW2997574754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.