Evidence map›Paper›PMID 31906023›Full record

ReviewCells2019

Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment.

Esperanza R Matarredona, Angel M Pastor

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 95 citations in OpenAlex.

  1. Extracellular vesicles: Navigating new frontiers in glioblastoma therapy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
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  12. Glioma-Derived Exosomes and Their Application as Drug Nanoparticles.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Review
  15. Review
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  17. Impact of hypoxia on the molecular content of glioblastoma-derived exosomes.Extracellular vesicles and circulating nucleic acids · 2024
    Review
  18. Review
  19. Article
  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Esperanza R MatarredonaDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain.
Angel M PastorDepartamento de Fisiología, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain.
Universidad de Sevilla · ES

Funding

Database development and modeling of signal transductionF33CA094654 · NCI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI SCHEUERMANN, RICHARD H · 2002 to 2002
$19k
Ministerio de Ciencia, Innovación y Universidades PGC2018-094654-B-100
6 · The paper itself

Abstract

The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit. Among these, extracellular vesicles have emerged as a focus of study in the last few years. Extracellular vesicles contain soluble proteins, DNA, mRNA and non-coding RNAs with which they can modulate the phenotypes of recipient cells. In this review we summarize recent findings on the extracellular vesicles-mediated bilateral communication established between glioblastoma cells and their tumor microenvironment, and the impact of this dialogue for tumor progression and recurrence.

Indexed as

AnimalsBrain NeoplasmsCell CommunicationExosomesExtracellular VesiclesGlioblastomaHumansMicroRNAsNeoplasm Recurrence, LocalTumor MicroenvironmentMicroRNAsexosomesglioma stem cellsmicrovesiclestumor microenvironment

Identifiers

PMID31906023
PMCPMC7017035
OpenAlexW2997236641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.