Evidence map›Paper›PMID 31905954›Full record

ArticleDiagnostics (Basel, Switzerland)2019

Cerebral Microbleeds in a Stroke Prevention Clinic.

A-Hyun Cho, Lara Wadi, Daniel Chow, Peter Chang, David Floriolli, Krunal Shah, Annlia Paganini-Hill, Mark Fisher

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Mechanisms of Cerebral Microvascular Disease in Chronic Kidney Disease.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

A-Hyun ChoDepartment of Neurology, University of California, Irvine, Orange, CA 92868, USA.
Lara WadiDepartment of Neurology, University of California, Irvine, Orange, CA 92868, USA.
Daniel ChowDepartment of Radiological Sciences, University of California, Irvine, Orange, CA 92868, USA.
Peter ChangDepartment of Radiological Sciences, University of California, Irvine, Orange, CA 92868, USA.
David FloriolliDepartment of Radiological Sciences, University of California, Irvine, Orange, CA 92868, USA.
Krunal ShahDepartment of Neurology, University of California, Irvine, Orange, CA 92868, USA.
Annlia Paganini-HillDepartment of Neurology, University of California, Irvine, Orange, CA 92868, USA.ORCID 0000-0003-4106-3334
Mark FisherDepartment of Neurology, University of California, Irvine, Orange, CA 92868, USA.
University of California, Irvine · US

Funding

HEMORHOLOGICAL FACTORS IN CEREBRAL ISCHEMIAR01NS020989 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRIBBS, DAVID HASTINGS, FISHER, MARK J · 1985 to 2022
$9.1M
NIH HHS NS20989NINDS NIH HHS R01 NS020989
6 · The paper itself

Abstract

The objective of this study is to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January 2011 and March 2017. Susceptibility-weighted imaging (SWI) MRI studies were obtained at baseline and follow-up visits to identify new infarctions and CMB progression. Patients with CMB who also underwent brain computed tomography (CT) imaging were identified and their cerebral arterial calcification was quantified to evaluate the relationship between the extent of intracranial calcification and CMB burden. A total of 64 stroke patients (mean age 73.1 ± 11.0, 47% males) had CMB on baseline and follow-up MRI studies. During a mean follow-up period of 22.6 months, four strokes occurred (4/64, 6%; 3 ischemic, 1 hemorrhagic), producing mild neurological deficit. Progression of CMB was observed in 54% of patients with two MRIs and was significantly associated with length of follow-up. Subjects with intracranial calcification score > 300 cm

Indexed as

cerebral microbleedscerebrovascular disease/strokeCTinfarctionMRIstroke prevention

Identifiers

PMID31905954
PMCPMC7168200
OpenAlexW2997756111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.