Evidence map›Paper›PMID 31905844›Full record

ArticleInternational journal of molecular sciences2019

Carbonic Anhydrase IX-Mouse versus Human.

Martina Takacova, Monika Barathova, Miriam Zatovicova, Tereza Golias, Ivana Kajanova, Lenka Jelenska, Olga Sedlakova, Eliska Svastova, Juraj Kopacek, Silvia Pastorekova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Martina TakacovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Monika BarathovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Miriam ZatovicovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Tereza GoliasBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0001-5386-1478
Ivana KajanovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Lenka JelenskaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Olga SedlakovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Eliska SvastovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Juraj KopacekBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.
Silvia PastorekovaBiomedical Research Center, Institute of Virology, Department of Tumor Biology, Slovak Academy of Sciences, Dubravska cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0001-8203-405X
Biomedical Research Center of the Slovak Academy of Sciences · SK

Funding

Research & Developmental Support Agency APVV-15-0697Research & Development Operational Program funded by the European Regional Development Fund ITMS26240220087, ITMS 2014+:313011T444Slovak Scientific Grant Agency (VEGA) 2/0122/16, 2/0076/20,VEGA 2/0074/20,VEGA 2/0133/16
6 · The paper itself

Abstract

In contrast to human carbonic anhydrase IX (hCA IX) that has been extensively studied with respect to its molecular and functional properties as well as regulation and expression, the mouse ortholog has been investigated primarily in relation to tissue distribution and characterization of CA IX-deficient mice. Thus, no data describing transcriptional regulation and functional properties of the mouse CA IX (mCA IX) have been published so far, despite its evident potential as a biomarker/target in pre-clinical animal models of tumor hypoxia. Here, we investigated for the first time, the transcriptional regulation of the

Indexed as

Gene Expression RegulationAnimalsAntigens, NeoplasmBinding SitesCarbonic Anhydrase IXCell AdhesionCell MovementExosomesHumansHydrogen-Ion ConcentrationHypoxiaMicePromoter Regions, GeneticProtein DomainsAntigens, NeoplasmCA9 protein, humanCar9 protein, mouseCarbonic Anhydrase IXcarbonic anhydrase IXexosomeshypoxiamigrationpH regulationtranscriptional regulation

Identifiers

PMID31905844
PMCPMC6982145
OpenAlexW2998479529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.