Evidence map›Paper›PMID 31905831›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Protective Role of Peroxiredoxins against Reactive Oxygen Species in Neonatal Rat Testicular Gonocytes.

Cristian O'Flaherty, Annie Boisvert, Gurpreet Manku, Martine Culty

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  11. Reactive Oxygen Species and Male Fertility.Antioxidants (Basel, Switzerland) · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Cristian O'FlahertyThe Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.ORCID 0000-0001-8884-1274
Annie BoisvertThe Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
Gurpreet MankuThe Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
Martine CultyThe Research Institute of the McGill University Health Centre, Montreal, QC H4A 3J1, Canada.
McGill University Health Centre · CAUniversity of Southern California · US

Funding

CIHR MOP-133456CIHR MOP-133661Natural Sciences and Engineering Research Council of Canada Discovery Grant # 386038-2013School of Pharmacy, University of Southern California Research Funds
6 · The paper itself

Abstract

Peroxiredoxins (PRDXs) are antioxidant enzymes that protect cells from oxidative stress and play a role in reactive oxygen species (ROS)-mediated signaling. We reported that PRDXs are critical for human fertility by maintaining sperm viability and regulating ROS levels during capacitation. Moreover, studies on Prdx6

Indexed as

differentiationgonocytesoxidative stressperoxiredoxinsROStestis

Identifiers

PMID31905831
PMCPMC7022870
OpenAlexW2996967327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.