Evidence map›Paper›PMID 31905822›Full record

ArticleInternational journal of molecular sciences2019

Difference in Developmental Kinetics of Y-Specific Monoclonal Antibody Sorted Male and Female In Vitro Produced Bovine Embryos.

Tabinda Sidrat, Rami Kong, Abdul Aziz Khan, Muhammad Idrees, Lianguang Xu, Marwa El Sheikh, Myeong-Don Joo, Kyeong-Lim Lee, Il-Keun Kong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

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  7. Mitochondrial dysfunction in pregnancy loss: a review.Molecular and cellular biochemistry · 2025
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  9. SGLT2 inhibitors: how do they affect the cardiac cells.Molecular and cellular biochemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Tabinda SidratDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Rami KongGyeongsang Animal Science Technology (GAST), Gyeongsang National University; Jinju-daero 501, Korea.
Abdul Aziz KhanCenter for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ 07110, USA.
Muhammad IdreesDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.ORCID 0000-0002-9715-0691
Lianguang XuDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Marwa El SheikhDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Myeong-Don JooDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Kyeong-Lim LeeDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.
Il-Keun KongDepartment of Animal Science, Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Gyeongnam, Korea.ORCID 0000-0001-5567-1088
Gyeongsang National University · KRHackensack University Medical Center · US

Funding

Ministry of Agriculture, Food and Rural Affairs MAFRA-117029-3 and 315017-5
6 · The paper itself

Abstract

Sex-related growth differences between male and female embryos remain an attractive subject for reproductive biologists. This study aimed to investigate the endogenous factors that play a crucial role in the pace of early development between male and female bovine embryos. Using sex pre-selected semen by Y-specific monoclonal antibodies for the production of bovine embryos, we characterized the critical endogenous factors that are responsible for creating the development differences, especially during the pre-implantation period between male and female embryos. Our results showed that at day seven, (57.8%) Y-sperm sorted in vitro cultured embryos reached the expanded blastocyst (BL) stage, whereas the X-sperm sorted group were only 25%. Y-BLs showed higher mRNA abundance of pluripotency and developmental competency regulators, such as

Indexed as

Y ChromosomeAnimalsAntibodies, MonoclonalBlastocystCattleEmbryo, MammalianEmbryonic DevelopmentFemaleGenes, X-LinkedGenes, Y-LinkedGlucoseKineticsMaleMembrane Potential, MitochondrialMitochondriaPhosphorylationAntibodies, MonoclonalGlucoseBovine blastocystdevelopmental kineticssex differencesY-specific monoclonal antibody

Identifiers

PMID31905822
PMCPMC6981608
OpenAlexW2998448588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.