Evidence map›Paper›PMID 31905814›Full record

ArticleBiology2019

Dawn to Dusk: Diurnal Rhythm of the Immune Response in Rainbow Trout (

Ruth Montero, Joanna Ewa Strzelczyk, Justin Tze Ho Chan, Marieke Verleih, Alexander Rebl, Tom Goldammer, Bernd Köllner, Tomáš Korytář

Open access · goldAbstract read
In one paragraph

Article in Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ruth MonteroFriedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Institute of Immunology, 17493 Greifswald-Insel Riems, Germany.
Joanna Ewa StrzelczykFriedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Institute of Immunology, 17493 Greifswald-Insel Riems, Germany.
Justin Tze Ho ChanInstitute of Parasitology, Biology Centre of the Czech Academy of Sciences, 37001 České Budějovice, Czech Republic.ORCID 0000-0003-4271-0177
Marieke VerleihLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, 18196 Dummerstorf, Germany.
Alexander ReblLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, 18196 Dummerstorf, Germany.ORCID 0000-0002-2918-7433
Tom GoldammerLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, 18196 Dummerstorf, Germany.ORCID 0000-0003-1215-5504
Bernd KöllnerFriedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Institute of Immunology, 17493 Greifswald-Insel Riems, Germany.
Tomáš KorytářInstitute of Parasitology, Biology Centre of the Czech Academy of Sciences, 37001 České Budějovice, Czech Republic.
Friedrich-Loeffler-Institut · DEResearch Institute for Farm Animal Biology (FBN) · DEInstitute of Parasitology · CZUniversity of South Bohemia in České Budějovice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The daily change of light and dark periods influences different physiological processes including feeding, resting and locomotor activity. Previously, several studies on mammalian models revealed a strong link between day-night rhythms and key immunological parameters. Since teleost fishes possess innate and adaptive immune responses like those observed in higher vertebrates, we aimed to elucidate how changes in light-dark cycles shape the immune system of fish. Using the rainbow trout laboratory model, we investigated the link between diurnal rhythms and immune competence of fish. Initially, the cell composition and phagocytic activity of leukocytes was analyzed in the circulation as well as in the head kidney, the functional ortholog of mammalian bone marrow. Once the baseline was established, we evaluated the ability of fish to respond to a bacterial stimulus, as well as the changes in antimicrobial activity of the serum. Our results suggest increased immune competence during the day, manifested by the higher presence of myeloid cells in the circulation; increased overall phagocytic activity; and higher capacity of the sera to inhibit the growth of

Indexed as

blood compositionchronoimmunologydiurnal rhythmmyeloid cellsphagocytic cells

Identifiers

PMID31905814
PMCPMC7168250
OpenAlexW2998129532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.